Anti-Doping And Medication Control Program: Q&A With Denali’s Craig Bandoroff

The Horseracing Integrity and Safety Authority released the following Q & A conducted with Craig Bandoroff of Denali Stud regarding questions that he submitted, as a supporter of HISA, about the Anti-Doping and Medication Control Program.

  1. Although I've read explanations and have had people try to explain it to me I still don't understand why we test to such a small level.  As I understand it a picogram is one-trillionth of a gram.  How can that have any effect on a 1200-lb horse?  Why do we test to such a small level?  Are we using the ARCI recommended guidelines?

It is important to remember that a picogram is a measure of weight, not potency. While some legal drugs are more potent and are administered in low doses, others are less potent and require larger doses to achieve their intended effects. This is why the Screening Limits used by HISA are different depending on the substance.

It is also important to note that substance concentrations are reported “per milliliter.” Thus, the picogram amounts you read in a lab report must be multiplied by approximately 50,000 to reflect the total milliliters of blood that can be found in a horse.

The Horseracing Integrity and Safety Act requires HISA to adopt the standards used by the International Federation of Horseracing Authorities (IFHA), which are followed in nations around the world and independent of the ARCI's guidance, as a starting point. The IFHA's Screening Limits and Thresholds are vetted by the European Horseracing Scientific Liaison Committee, which is composed of veterinary pharmacologists, regulatory veterinarians, chemists, and other racing regulators, before being approved by the IFHA. There are certain substances, e.g., phenylbutazone, for which the ADMC Standing Committee decided to deviate from the IFHA's published recommendations based on additional science and industry-specific insight.

  1. Everyone agrees the ultimate goal is to keep honest people honest and dishonest people afraid to break the rules.  And that the objective is not to penalize trainers and owners that make honest inconsequential mistakes but rather catch the cheaters. Are we doing enough to catch the cheaters and those taking advantage of the system?  The objective isn't to penalize honest trainers and subsequently their owners for honest mistakes that result in an insignificant overage and that don't affect a horse's performance, is it?

The Anti-Doping and Medication Control (ADMC) Program is designed to detect and deter those who intentionally try to break the rules, thus compromising the integrity of the sport and the welfare of equine and human athletes. The Program includes a test distribution plan that will focus on utilizing testing resources in a manner that will both detect and deter violations, including thorough intelligence-based target testing. 

In addition, sanctions associated with Anti-Doping Rule Violations, which include the use or administration of substances that are prohibited from being present in a horse at any time (Banned Substances), are intended to be harsh.  

However, there are significantly less severe penalties for offenses related to legal Controlled Medication Substances. For example, the penalty for a first offense related to a Class C medication such as phenylbutazone or methocarbamol is the disqualification of race-day results and a fine of up to $500. There is no suspension.

For many types of cases, direct penalties for the Covered Person(s) involved can be reduced or eliminated depending on the degree of fault determined by the adjudicator(s) hearing the case.

Promoting integrity of the competition and welfare of the horse are two key pillars of the ADMC Program. In support of these two principles, the regulations require that disqualifications are upheld for positive tests regardless of fault in acknowledgement of the fact that the integrity of the race and/or the welfare of the horse may have been compromised by the presence of a Prohibited Substance in the horse's system.

On a national scale, HIWU's team includes an investigations unit that will utilize data science, intelligence from local investigators and racing officials, e.g., stewards and regulatory veterinarians, and information received from HIWU's anonymous whistleblower platforms. This group's objectives are to identify and catch those who commit violations of the Program, especially the most egregious offenses. HIWU Director of Intelligence & Strategy Shaun Richards brings 23 years of experience with the FBI and initiated and directed the criminal investigation that ultimately resulted in the indictments of more than 30 individuals, including trainers Jorge Navarro and Jason Servis.

  1. What are we doing about positives that are possibly the result of contamination or human error? I was involved in a case that it seemed that the positive was a result of contamination at some point.  A Hall of Fame trainer with a pristine record had a horse test positive for a sedative drug he said he doesn't use and the horse was never given.  The horse ran his eyeballs out that day. My owner lost the $40,000 purse. We think the sample was contaminated or perhaps nefarious behavior took place, or someone along the chain of testing made a mistake.  I guess a positive is a positive and if you break the rules you are going to be penalized.  Even so, that's not what we should be trying to do in regulating horse racing, is it?  Do we have anything in place to address these types of situations?

The ADMC Program includes an Atypical Findings Policy that is intended to address cases of environmental contamination.  Under this Policy, if a laboratory detects the presence of the following types of substances, it will report the result as “Atypical,” NOT “positive”:

  1. Specified Substances that pose a higher risk of being present due to environmental contamination, e.g., caffeine, cannabinoids, ractopamine, scopolamine, zilpaterol;
  2. Endogenous substances, e.g., testosterone; or
  3. Substances that pose a high risk of contamination but have yet to be identified.

When an Atypical Finding is issued, an investigation will be launched by HIWU, and the horse's trainer and/or owner will have the opportunity to provide information that can explain the presence of the substance. Examples of evidence could include proof that the horse consumed feed or bedding that was shown to have been contaminated with the substance in question. The trainer could also provide veterinary evidence indicative of the levels of the substance present in the horse naturally.

If HIWU determines that the Atypical Finding was due to environmental contamination and/or that the substance was not exogenously administered based on information gathered, the laboratory result will be considered negative, and no further action will be taken in connection with the result. Consequently, there will be no loss of purse money or imposition of any other sanctions.

The Atypical Findings Policy is intended to protect trainers from being punished for substance exposures beyond their control. 

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HISA Medication Rules: Withdrawal Guidelines Released By Racing Medication And Testing Consortium

The Racing Medication and Testing Consortium's Scientific Advisory Committee has performed an analysis of HISA's proposed Anti-Doping and Medication Control program (ADMC) and, where data permits, developed withdrawal guidance associated with the ADMC Screening Limits and Detections Times of the schedule of RMTC Controlled Therapeutic Substances (CTS).

Among the guidelines issued for non-steroidal anti-inflammatories, the shortest recommended withdrawal time is for Ketoprofen at 72 hours (at 2.2 mg/kg single IV dose). The other two NSAIDs for which guidelines were issued, Flunixin Meglumine (Banamine) and Phenylbutazone (Bute), have withdrawal times of at least 96 hours (IV administration).

The withdrawal guidance is available here: https://rmtcnet.com/wp-content/uploads/2023/03/2023-03.20-RMTC-Withdrawal-Guidance-of-ADMC.pdf

Withdrawal guidelines are for informational purposes only. It is advisable that this information should be used by horsemen in consultation with their attending veterinarian. The withdrawal guidelines do not constitute a guarantee or warranty.

HISA's expected ADMC implementation date is March 27, 2023.

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Equine Injury Database: Statistics Show Decreasing Fatality Rate For Fourth Straight Year

The initial data analysis from the 14th year of reporting to the Equine Injury Database (EID) shows a decrease in the rate of fatal injury in 2022 (1.25 fatalities per 1,000 starts) compared to 2021 (1.39 fatalities per 1,000 starts). This is the fourth consecutive year that the rate has decreased, and it is the third consecutive year in which the rate has been below 1.5 fatalities per 1,000 starts. It is the first time ever that the rate has been below 1.3 fatalities per 1,000 starts.

Analysis provided by Professor Tim Parkin (University of Bristol), who has consulted on the EID since its inception, and by Dr. Euan Bennet (University of Glasgow), also shows historic low rates of fatality on each surface type, for 3-year-old horses, and for race distances longer than 8 furlongs.

“The data shows that since 2009, the risk of fatal injury during racing has declined by 37.5%, which is statistically significant,” Parkin said. “The overall downward trends are testament to the benefits of an evidence-based approach to safety, which is only possible thanks to the EID.”

Statistical Summary from 2009 to 2022

(Thoroughbred Flat Racing Only)

Calendar

Year

2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Rate 2.00 1.88 1.88 1.92 1.90 1.89 1.62 1.54 1.61 1.68 1.53 1.41 1.39 1.25

Based on the 2022 data, 99.88% of flat racing starts at the racetracks participating in the EID were completed without a fatality.

Key statistics from the 2022 analysis are as follows (figures represent the incidence of racing fatality per 1,000 starts):

  • By age
    • 2-year-old:        0.98
    • 3-year-old:        1.13
    • 4+-year-old:      1.34
  • By race distance
    • <6 furlongs:      1.38
    • 6 – 8 furlongs:  1.31
    • >8 furlongs:      0.86
  • By track surface
    • Dirt:                  1.44
    • Turf:                 0.99
    • Synthetic:         0.41

For trends of the EID since 2009, please visit jockeyclub.com/pdfs/eid_14_year_tables.pdf.

Risk of fatal injury on the racecourse decreased by 10.1% from 2021 to 2022, 11.3% from 2020 to 2022, and 18.3% from 2019 to 2022.

“We can say with confidence that the risk of fatal injury is heading in a sustained downward direction both overall and in many specific areas,” Parkin said. “The six-month period from July 1, 2022, to December 31, 2022, was the safest six-month period on record since the inception of the EID in 2009. This evidence of positive progress is very encouraging and should be applauded by everyone in North American racing.”

Since March 2012, racetracks have been able to voluntarily publish their statistics from the EID on The Jockey Club website. The racetracks that publish their EID statistics reported racing fatalities per 1,000 starts of 0.99 as compared to 1.42 for those that do not publish.

The EID statistics are based on injuries that resulted in fatalities within 72 hours from the date of the race. The statistics are for official Thoroughbred races only and exclude steeplechase races. Summary statistics for the EID are subject to change due to a number of considerations, including reporting timeliness. All data entered into the EID goes through a multilevel quality control process to ensure the data is completely and accurately reported.

The list of racetracks participating in the EID and detailed statistics from those tracks that voluntarily publish their results can be found at jockeyclub.com/default.asp?section=Advocacy&area=11.

Throughout the course of 2022, approximately 99% of all Thoroughbred starts were included in the EID.

The Equine Injury Database, conceived at the Grayson-Jockey Club Research Foundation's first Welfare and Safety of the Racehorse Summit, was launched by The Jockey Club in July 2008 and seeks to identify the frequencies, types, and outcomes of racing injuries using a standardized format that generates valid statistics, identifies markers for horses at increased risk of injury, and serves as a data source for research directed at improving safety and preventing injuries.

The Jockey Club, founded in 1894 and dedicated to the improvement of Thoroughbred breeding and racing, is the breed registry for North American Thoroughbreds. In fulfillment of its mission, The Jockey Club, directly or through subsidiaries, provides support and leadership on a wide range of important industry initiatives, and it serves the information and technology needs of owners, breeders, media, fans and farms. It is the sole funding source for America's Best Racing, the broad-based fan development initiative for Thoroughbred racing. You can follow America's Best Racing at americasbestracing.net. Additional information is available at jockeyclub.com.

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CHRB Approves Redirection Of ADW Purse Revenue To Cover HISA Fee

The California Horse Racing Board conducted a meeting on Thursday, March 16, at the Le Meridien Hotel in Arcadia. Chairman Gregory Ferraro chaired the meeting, joined by Vice Chair Oscar Gonzales and Commissioners Dennis Alfieri, Damascus Castellanos, Brenda Washington Davis, and Thomas Hudnut.

The audio of this entire Board meeting is available on the CHRB Website (www.chrb.ca.gov) under the Webcast link. In brief:

— At the request of the Thoroughbred Owners of California (TOC) and racetracks, the Board approved a redirection of revenue from Advance Deposit Wagering that would normally go to Thoroughbred purses and commissions in order to pay the balance of California's 2023 fee to the Horseracing Integrity and Safety Authority (HISA). In expectation that step two of HISA's program will go into effect as scheduled on March 27,  California's proportional share of HISA's operating budget is $6,729,297. Largely through the efforts of CHRB staff, HISA is crediting California for the equine drug testing and research program that California will continue to pay for and perform on behalf of HISA, as well as sample collection, out-of-competition testing, and investigations, reducing the fee to $1,579,297. CHRB Deputy Executive Director Cynthia Alameda has been a principal in this cooperative effort with HISA. Commissioner Davis thanked CHRB Executive Director Scott Chaney and staff for a “job well done” in obtaining the credits.

CHRB and industry leaders helped guide HISA in the drafting of rules covering safety and drug testing, so HISA's rules largely reflect California's existing program, meaning California licensees will not experience much change under HISA. However, in his report to the Board, Chaney pointed out one major difference. Under HISA, which only regulates Thoroughbred racing, any drug testing positive on a post-race sample will result in the automatic disqualification of the horse and redistribution of the purse. The applicable HISA rules under section 3220 are Rules 3221 and 3321, Disqualification of the Covered Horse Results (a) Automatic Disqualification of Results.

Currently in California, disqualification only occurs for the most serious Classes 1, 2, and 3 infractions. Under HISA after March 27, what California classifies as Classes 4 and 5 violations also will require disqualification. Dr. Jeff Blea, the CHRB's equine medical director, reported there were four Class 4 violations (for methocarbamol and phenylbutazone overages) in January and February, but as those were out-of-competition samples, not post-race, there was no race result from which they could have been disqualified under HISA even had they occurred after March 27.

— Staff reported on the possibility of asking the Board to strengthen the CHRB's existing Inclement Weather Policy, primarily to further limit training activities on the main track and training track after inclement weather has forced those surfaces to be sealed (packed down to prevent seepage of water into the cushion). Training is the major focus because far more horses exercise in the morning than race in the afternoon and night, so training poses the greatest risk when surfaces have been unsealed but not yet fully settled. California racing executives have voluntarily canceled more than a dozen racing programs this year due to heavy rains.

— After stakeholders in Northern California reported they had not been able to reach agreement over a disputed week of racing despite months of negotiations, the commissioners made the decision for them by allocating the fourth week of August to both Golden Gate Fields and the Humboldt County Fair, meaning both tracks will run racing programs simultaneously (overlapped) in 2023. Vice Chair Gonzales cast the only negative vote in that decision. This action finalized all 2023 dates allocations in the state.

— The commissioners voted to withdraw their support for legislation, at least for this year, which would provide greater statutory funding for jockey welfare and backstretch medical services after representatives of the Jockeys' Guild and California Thoroughbred Horsemen's Foundation reported they will have sufficient funding for at least one or two more years, largely through assurances by the TOC and other supporters.

— Chaney reported on progress to hinder match racing at non-sanctioned locations in California. People for the Ethical Treatment of Animals (PETA) and other animal rights advocates have contributed to this effort.

— Representatives of Race Track Chaplaincy of America gave a presentation on their program, which ministers to the spiritual, emotional, physical, social, and educational needs of those persons involved in all aspects of the horse-racing industry.

— The Board authorized four of the racing fairs in Northern California to run their racing programs as one longer race meet for pari-mutuel purposes.

— The Board authorized distributions of race day charity proceeds by the Del Mar Thoroughbred Club, Santa Anita, and Golden Gate Fields to designated beneficiaries. Notably, Del Mar voluntarily contributed an additional $62,337 to its distributions. A representative of 1/ST Racing (formerly Stronach Group, owner of Santa Anita and Golden Gate) reported they contribute hundreds of thousands to charitable efforts beyond the statutory requirements in California.

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