Do Fatty Acids Benefit Foals In Utero?

Omega-3 fatty acids have many favorable health effects on horses, including joint, respiratory, and reproductive benefits. Supplementing pregnant mares with omega-3s late in gestation has advantages for their developing foals. However, not all types of omega-3 supplements fed to mares have the same effectiveness.

The two major sources of omega-3 fatty acids for horses are:

Plant-derived short-chain omega-3 fatty acids, primarily alpha linoleic acid (ALA). High levels of ALA are found in flaxseed, canola oil, and other feedstuffs, but ALA must be converted by the horse to long-chain omega-3 fatty acids, including DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) for optimal use by horses.

Marine-derived omega-3s rich in the specific omega-3 fatty acids DHA and EPA. Providing a direct source of these omega-3 fatty acids may be preferred, as the conversion of ALA to long-chain fatty acids is limited in horses.

No study has determined if the omega-3s offered in a mare's diet actually reaches her unborn foal.

To fill this knowledge gap, researchers recently designed a study to measure omega-3 fatty acid levels in foals from supplemented mares. Three diets that provided a similar total amount of omega-3 fatty acids from two different sources were used. The first was a control diet, the second was the control diet plus a commercial flaxseed supplement, and the third was the control diet with a commercial marine-derived omega-3 supplement.

When mares were offered each of these supplements during the last 30 days of gestation, only marine-derived supplementation resulted in a significant increase in DHA levels in foals.

The DHA measured in blood samples from foals born to mares offered only the control diet was 0.6 g/100 g of lipid (fat). In the foals from mares supplemented with the marine-derived omega-3, the DHA was significantly higher at 1.9 g/100 g lipid.

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“No difference in foal DHA blood levels was observed between the control and flaxseed diets, which means these results support the recommendation to provide a direct source of DHA and EPA due to the low conversion rate of ALA to DHA,” relayed Catherine Whitehouse, M.S., a nutritionist for Kentucky Equine Research.

Even though mares were supplemented during the first five days after foaling and foals were nursing those mares, DHA levels declined rapidly. By day five, DHA levels were similar across all diets. On day 30, which was 25 days after the mares were no longer supplemented, the DHA blood level of the foals was only 0.1 g/100 g lipid.

“Continuing to supplement mares throughout nursing until weaning may help maintain higher DHA levels in foals after foaling, providing long-term advantages to growth and development,” suggested Whitehouse.

EO-3, a marine-derived omega-3 supplement developed by Kentucky Equine Research, provides research-proven levels of DHA and EPA, can be top-dressed onto feed easily.

*Snyder, J. N. Shost, R. Miller, K. Fikes, R. Smith, B. Corl, A. Wagner, I. Girard, and J. Suagee-Bedore 2021. Late gestation supplementation of long-chain fatty acids increases foal docosahexaenoic acid concentrations at birth. Journal of Equine Veterinary Science 100:103522.

Article reprinted courtesy of Kentucky Equine Research (KER). Visit equinews.com for the latest in equine nutrition and management, and subscribe to The Weekly Feed to receive these articles directly (equinews.com/newsletters).   

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Peat Moss Or Wood Shavings: Bedding For Asthmatic Horses

The natural dust and molds found in bedding material often intensify the clinical signs of horses with asthma. Bedding materials differ in the inhalable and respirable particles they release, just as they have variable absorptive qualities and aesthetic appeal. While horsemen the world over use straw and wood shavings extensively, the popularity of peat moss often coincides with where it is easily obtained, such as in Nordic and Baltic countries. Finnish researchers recently investigated if the use of wood shavings and peat moss as bedding had different effects on the respiratory health of horses.

Researchers chose 32 clinically healthy riding-school horses for this study. The daily schedule of the horses included 18 hours in a stall, 2 to 3 hours of exercise in an indoor arena, and 3 to 4 hours outside in sandy paddocks. Horses were stabled in identically sized stalls with a common airspace and with the same level of ventilation. Researchers maintained bedding at a depth of approximately 4 inches, with new bedding added each day after stall cleaning to keep the depth consistent. Horses stayed on each bedding material for 35 days. Diets consisted of haylage and pelleted concentrate. Horses ate the haylage off the stall floor. Researchers performed lower airway endoscopy and sampling (tracheal wash and bronchoalveolar lavage fluid) for cytological examination at the end of each bedding period.

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While researchers found no differences in respiratory rate or tracheal mucus accumulation between treatments, horses bedded on wood shavings had more neutrophils in their tracheal washes and bronchoalveolar lavage fluid. The researchers concluded that “between the two bedding materials used in this study, peat caused less neutrophilic lower airway inflammation in horses.”

Asthmatic horses should be kept outside as much as possible, a management strategy that keeps many horses from having severe symptoms of asthma. High-performance horses must often be stabled to accommodate training and competition schedules. In these instances, medical management of asthma should be guided by a veterinarian well versed in the respiratory care of horses. Management decisions are often based on reducing inhalable dust and molds, which includes careful selection of bedding and forages.

Aside from forage type (haylage versus dry hay) or treatment (soaking versus high-temperature steaming), another nutritional consideration is the use of long-chain omega-3 fatty acids, particularly docosahexaenoic acid (DHA). In a consensus statement from the American College of Veterinary Internal Medicine, experts recommend the use of omega-3 fatty acids as a way to control airway inflammation.° The most potent sources of omega-3 fatty acids available for horses are marine-derived oils, such as EO-3.

*Monki, J., M. Sasstamoinen, N. Karikoski, M. Rajamaki, M. Roaekallio, J. Junnila, S. Sarkjarvi, M. Norring, A. Valros, S. Oranen Ben Fatma, and A. Mykkanen. 2021. Effects of bedding material on equine lower airway inflammation: A crossover study comparing peat and wood shavings. Frontiers in Veterinary Science 8:656814.

Read more here.

Reprinted courtesy of Kentucky Equine Research. Visit ker.com for the latest in equine nutrition and management, and subscribe to Equinews to receive these articles directly.

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Omega-3s And Inflammation In Athletic Horses

Inflammation is part and parcel to building strength and fitness in equine athletes. One key to training, however, is keeping inflammation at controllable levels after exercise so recovery occurs quickly and training continues unhindered. New findings from Kentucky Equine Research (KER) suggest long-chain omega-3s may be useful in managing inflammation in hard-working horses.

Using eight Thoroughbreds in race training, the researchers designed a 28-day study to determine the effect of long-chain omega-3 (EO-3) supplementation and exercise on blood serum gamma-glutamyl transferase (GGT) levels and inflammation. The enzyme GGT breaks down glutathione, a potent antioxidant. As levels of GGT rise, less glutathione is available to neutralize free radicals, leaving more cells susceptible to the damaging effects of oxidation.

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“Interest in the effect of omega-3s on inflammation stemmed from consistently high concentrations of the enzyme GGT in blood samples of some racing Thoroughbreds,” said Laura Petroski-Rose, B.V.M.S., a veterinarian with Kentucky Equine Research.

In the study, four of the horses were supplemented daily with 60 mL (2 ounces) of EO-3, while four horses served as controls and received the same feed without EO-3. All horses were fed 13to 15 pounds (6-7 kg) of a commercial racing feed (12 percent protein, 8 percent fat) with free-choice timothy hay. During the study, the horses were galloped three times per week (1-1.5 miles per session) on a racetrack and jogged three times per week (30 minutes per session) on a mechanical exerciser. At the conclusion of the 28 days, the horses performed an exercise test on the racetrack that consisted of a warm-up jog, ten-furlong (2,000-meter) gallop, and a two-furlong (400-meter) breeze. Blood samples were taken before exercise as well as two and four hours post-exercise.

The horses supplemented with EO-3 had significantly lower GGT levels two and four hours post-exercise compared to the control horses. This may have resulted from a reduction in inflammation observed post-exercise in the horses fed EO-3. Read more about the study.

Read more here.

Reprinted courtesy of Kentucky Equine Research. Visit ker.com for the latest in equine nutrition and management, and subscribe to Equinews to receive these articles directly.

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Flaxseed Oil Boasts Measurable Horse Health Benefits

Supplementing oil to a horse's diet can be done with a variety of oils for a multitude of reasons, but a recent study has found that feeding flaxseed oil to horses is a healthier option than feeding soybean oil.

Common oils fed to horses include soybean, corn, rapeseed, fish and flaxseed. The quality of the fat used is important in equine nutrition. Flaxseed oil is high omega-3 polyunsaturated fatty acids and has a good ratio of omega-6 to omega-3. However, excess intake of polyunsaturated fatty acids may increase the risk of oxidation reactions, which can lead to imbalances and oxidative stress, which can be harmful for the horse.

Drs. Iwona Sembratowicz, Grzegorz Zięba, Ewelina Cholewinska and Anna Czech wanted to test if supplementing a horse's diet with flaxseed oil reduced oxidative stress and positively influenced blood biomarkers.

The scientists used 40 healthy horses in the study: 20 mares and 20 stallions. The horses were divided into two similar groups; they were stalled separately and kept in light work. All horses received hay and oats with a ration balancer in their morning feed. Both sets of horses were orally administered oil via a syringe after their morning meal: The control group received soybean oil and the experimental group received the same amount of flaxseed oil.

After 60 days, blood was drawn before the horses ate breakfast. The study team found that the horses fed flaxseed oil had better lipid profiles, improved blood parameters and better antioxidant mechanisms than those horses that were given soybean oil. The flaxseed also significantly lowered plasma glucose levels and increased antioxidant indices and red blood cell indicators.

The scientists concluded that switching a horse from soybean oil to flaxseed oil was beneficial to its health.

Read the study here.

Read more at HorseTalk.

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