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Study Shows Possible Link Between Equine Obesity And Asthma

It's been proven that carrying extra pounds can cause humans to develop asthma, and researchers are now attempting to find a link between obesity and breathing issues in horses.

Texas A&M and the Morris Animal Foundation are funding research on the debilitating condition. Currently, the main treatment option for asthmatic horses is the use of corticosteroids, which can cause laminitis in overweight equines.

Texas A&M researcher Dr. Michelle Coleman intends to use 60 horses brought to the University's veterinary teaching hospital for the study. The research team will assess each horse's body condition, identify if they have insulin issues, and determine their asthmatic state by listening to their lungs and taking fluid samples from their lower airways. The horses will be divided into four groups of 15: Obese and asthmatic, non-obese and asthmatic, obese and healthy, and non-obese and healthy.

Each group will be examined for inflammation markers, including cytokine levels. The cytokine levels in humans differ between obese asthmatic people and non-obese asthmatic people. The study will also look at each horse's lung microbiota to see if there is a difference in obese asthmatic horses and non-obese asthmatic horses.

Researchers hope the results from the study will allow horse owners and veterinarians to identify horses at higher asthmatic risk and assist in preventing asthma or intervening in such situations earlier.

FDA Approves First Generic Ketoprofen For Use In Horses

The FDA has approved KetoMed, the first generic ketoprofen for the alleviation of inflammation and pain associated with musculoskeletal disorders in horses.

Musculoskeletal disorders are prevalent in aging horses and can cause pain, weakness, stiffness and decreased range of motion in the animals' joints. Osteoarthritis and chronic laminitis are among the most common musculoskeletal disorders in horses and can greatly impact a horse's performance and quality of life.

KetoMed contains the same active ingredient (ketoprofen) in the same concentration and dosage form as the approved brand name drug product, Ketofen, which was first approved on September 26, 1990. In addition, the FDA determined that KetoMed contains no inactive ingredients that may significantly affect the bioavailability of the active ingredient.

The data submitted in support of the Abbreviated New Animal Drug Application demonstrate that KetoMed, when used according to its label, is safe and effective.

KetoMed is a prescription product because a veterinarian's expertise is required to diagnose musculoskeletal disorders and to determine whether ketoprofen is an appropriate treatment.

KetoMed is supplied in 50 mL and 100 mL multidose bottles. The recommended dosage is 1 mg/lb (1 mL/100 lbs) of body weight once daily. Treatment is administered by intravenous injection and may be repeated for up to five days.

KetoMed is sponsored by Bimeda Animal Health Ltd. based in Dublin, Ireland.

Elevate Heels To Alleviate Laminitic Pain

Very few equine conditions can be as debilitating as laminitis, which can be triggered by a variety of events or occur on its own. Laminitis occurs when the laminae, a set of finger-like structures which support the coffin bone and hold it in place in the hoof capsule, become inflamed. This inflammation is incredibly painful.

The breakover phase of a horse's stride is the most painful for laminitis horses. This is when all of his weight rests on his toe as he steps forward, putting intense pressure on already-sensitive structures. A study has found that elevating a horse's heels with a wedge can shorten the breakover period, protecting damaged tissues and helping to alleviate some of the horse's pain.

The study used eight acutely laminitic horses to compare the breakover of hooves and those with a heel wedge. The horses were walked on a poured concrete surface both barefoot and with the wedge applied. The scientists found that the heel wedge shortened breakover and reduced the load on the horse's toe. Elevating the heel placed 81 percent of the load on the bottom half of the hoof, near the heel, relieving pain and mitigating lamellar damage.

The researchers recommend using heel wedges for no more than two to three weeks at a time to avoid collapsing the horse's heels and contracting his hooves.

Laminitis Claims Young Sire Fast Anna At Age 10

Fast Anna, a Grade 1-placed runner and young sire, was euthanized Monday due to complications from laminitis.

Tom Hamm, director of nominations and sales at Three Chimneys, said the 10-year-old son of Medaglia d'Oro had been struggling with the disease for a month.

Fast Anna has sired three crops of racing age, with 45 winners and combined progeny earnings of more than $2.6 million. He has sired six stakes winners, led by Been Studying Her, a two-time stakes winner in California who has earned $305,602.

During his own on-track career, Fast Anna won three of nine starts and earned $296,731. He won the Sawgrass Handicap on turf, while on dirt, he finished second in the Grade 1 King's Bishop Stakes and G3 Gallant Bob Stakes.

Bred in Kentucky by Frank Calabrese, Fast Anna is out of the champion Rahy mare Dreaming of Anna. He hailed from the family of champion and leading sire Kitten's Joy, and graded stakes winners Precious Kitten, Lewis Michael, and Justenuffhumor.

The post Laminitis Claims Young Sire Fast Anna At Age 10 appeared first on Horse Racing News | Paulick Report.

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