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Do Fatty Acids Benefit Foals In Utero?

Omega-3 fatty acids have many favorable health effects on horses, including joint, respiratory, and reproductive benefits. Supplementing pregnant mares with omega-3s late in gestation has advantages for their developing foals. However, not all types of omega-3 supplements fed to mares have the same effectiveness.

The two major sources of omega-3 fatty acids for horses are:

Plant-derived short-chain omega-3 fatty acids, primarily alpha linoleic acid (ALA). High levels of ALA are found in flaxseed, canola oil, and other feedstuffs, but ALA must be converted by the horse to long-chain omega-3 fatty acids, including DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) for optimal use by horses.

Marine-derived omega-3s rich in the specific omega-3 fatty acids DHA and EPA. Providing a direct source of these omega-3 fatty acids may be preferred, as the conversion of ALA to long-chain fatty acids is limited in horses.

No study has determined if the omega-3s offered in a mare's diet actually reaches her unborn foal.

To fill this knowledge gap, researchers recently designed a study to measure omega-3 fatty acid levels in foals from supplemented mares. Three diets that provided a similar total amount of omega-3 fatty acids from two different sources were used. The first was a control diet, the second was the control diet plus a commercial flaxseed supplement, and the third was the control diet with a commercial marine-derived omega-3 supplement.

When mares were offered each of these supplements during the last 30 days of gestation, only marine-derived supplementation resulted in a significant increase in DHA levels in foals.

The DHA measured in blood samples from foals born to mares offered only the control diet was 0.6 g/100 g of lipid (fat). In the foals from mares supplemented with the marine-derived omega-3, the DHA was significantly higher at 1.9 g/100 g lipid.

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“No difference in foal DHA blood levels was observed between the control and flaxseed diets, which means these results support the recommendation to provide a direct source of DHA and EPA due to the low conversion rate of ALA to DHA,” relayed Catherine Whitehouse, M.S., a nutritionist for Kentucky Equine Research.

Even though mares were supplemented during the first five days after foaling and foals were nursing those mares, DHA levels declined rapidly. By day five, DHA levels were similar across all diets. On day 30, which was 25 days after the mares were no longer supplemented, the DHA blood level of the foals was only 0.1 g/100 g lipid.

“Continuing to supplement mares throughout nursing until weaning may help maintain higher DHA levels in foals after foaling, providing long-term advantages to growth and development,” suggested Whitehouse.

EO-3, a marine-derived omega-3 supplement developed by Kentucky Equine Research, provides research-proven levels of DHA and EPA, can be top-dressed onto feed easily.

*Snyder, J. N. Shost, R. Miller, K. Fikes, R. Smith, B. Corl, A. Wagner, I. Girard, and J. Suagee-Bedore 2021. Late gestation supplementation of long-chain fatty acids increases foal docosahexaenoic acid concentrations at birth. Journal of Equine Veterinary Science 100:103522.

Article reprinted courtesy of Kentucky Equine Research (KER). Visit equinews.com for the latest in equine nutrition and management, and subscribe to The Weekly Feed to receive these articles directly (equinews.com/newsletters).

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Are Probiotics Worth The Hype?

Probiotics have their fair share of both devotees and naysayers. Why do the devotees keep probiotics in their medicine cabinet? For diarrhea, primarily. Approximately 80 percent of foals develop diarrhea sufficiently severe to threaten growth and, depending on its severity, survival. Adult horses develop diarrhea for several reasons, including physical and mental stress, disease, and certain medications.

Treating diarrhea medicinally may resolve the condition, but some medications have unwelcome side effects: inappetence, skin reactions (wheals, swelling), and kidney toxicity. The benefits of administering probiotics for treating or preventing diarrhea remain largely theoretical despite the widespread availability of the products.

To shed light on the actual, rather than perceived, benefits of probiotics in horses, Australian researchers conducted a thorough review of the available scientific literature. After combing through many relevant research papers, they selected 18 that examined the safety, tolerability, and efficacy of probiotics in horses and foals. Some of the key findings of this study were:

Probiotics appeared well tolerated in adult horses with few safety concerns;
Substantial concerns were noted in foals. High doses of multistrain probiotics appeared to aggravate diarrhea, particularly when products similar to those designed for humans were used. When the probiotic contained organisms more closely related to the microbes normally found in the equine microbiome, the incidence of foal diarrhea nearly halved; and
Single probiotic interventions appear less effective than multispecies probiotics.

In addition to managing diarrhea, owners sometimes give probiotics to horses whose diets contain large grain meals.

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“High-grain diets can disturb intestinal function, leading to hindgut acidosis, a condition characterized by unusually low pH in the cecum and colon. This drop in pH can change the microbiome, reducing digestibility of feed. Hindgut acidosis may result in loose manure, decreased appetite, behavior changes, colic, and laminitis,” explained Peter Huntington, B.V.Sc., M.A.C.V.Sc., director of nutrition at Kentucky Equine Research.

To combat plummeting pH in the hindgut, researchers looked at offering a probiotic to improve the microbiome and increase digestive function. However, two separate studies failed to identify any benefit in feeding a probiotic to horses given high-grain diets.

“This finding leaves room for more research and alternate approaches to controlling pH in the hindgut. Using hindgut buffers such as the research-proven hindgut supplements created by Kentucky Equine Research are potentially better than using probiotics for this purpose,” Huntington recommended.

While the role of probiotics for intestinal conditions remains unclear, researchers found beneficial effects of probiotics in exercising Standardbred horses. Specifically, those researchers stated that “administration of multistrain bacterial formulations to increase stamina in exercising horses shows promise.”

Huntington added, “Supplemented horses had lower blood lactate levels, which may delay fatigue in exercising horses. At this time, though, researchers are unclear as to how probiotics lower blood lactate levels.”

Also noteworthy, the number of studies examining probiotics in horses was extremely small compared to those for humans. As such, much of the information used to support probiotics intended for horses is actually extrapolated from human studies.

“The anatomy and physiology of the equine digestive tract are very different from that of the human, which makes data extrapolation inappropriate. Using human data for horses may at least partly explain the lack of reported efficacy of probiotics in horses,” Huntington said.

Instead of extrapolating from human medicine, scientists should consider equine-specific research, as many questions remain unanswered. For example, what species of bacteria and yeast should be included in probiotic supplements, and what multistrain products will have the most benefit? How much should be given? How long should horses be given the supplements?

Quality concerns also persist. Do commercial over-the-counter probiotics contain the type or amount of ingredient they claim? The live bacteria that went into the package or syringe may not be viable when actually fed, which negates its usefulness.

“While probiotics may exert positive gastrointestinal and extraintestinal effects, using poor-quality products or administering probiotics incorrectly may delay more appropriate treatments or interventions and are economically draining for horse owners,” summarized Huntington.

*Cooke, C.G., Z. Gibb, and J.E. Harnett. The safety, tolerability and efficacy of probiotic bacteria for equine use. Journal of Equine Veterinary Science 99:103407.

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Stave Off Rehab Setbacks With An Equine Motion Sensor

When an injury requires a horse to be on stall rest, the owner often has more time to fawn and fuss over it. Even the most devoted owner, however, cannot monitor her horse 24/7, and this means subtle changes in movement that could indicate a potential setback during recovery might go unnoticed. An inertial measurement unit (IMU) can help owners track the movement of stall-bound horses and help owners recognize when a complication might be looming.

“An IMU consists of small, wearable sensors that record information about a horse's movement, particularly the type, speed, and step count,” explained Catherine Whitehouse, M.S., a Kentucky Equine Research nutritionist. For many injuries, successful rehabilitation depends on a certain amount of movement. “Bearing weight during rehabilitation promotes circulation by delivering nutrients and oxygen to the injured tissues,” Whitehouse said.

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Decreased mobility of an injured horse during stall confinement could be an early indication of poorly managed pain or a potentially life-threatening complication. If identified early, specific interventions can be implemented, such as improved pain management and alterations in the rehabilitation protocol.

To assess the validity of a commercial IMU, a Canadian veterinary team recruited six horses.^* Sensors were placed at three different locations on the same horse (withers, right forelimb, and right hindlimb), and the horse's movements measured on the IMU were compared to direct observation.

“The data showed that the limb sensors accurately counted steps in stalled horses,” Whitehouse said. “The IMU proved itself a valuable tool in the early detection of movement reduction that could signal pain or complications and ultimately improve patient outcome.”

Another way to support horses during layup is by offering a nutritional supplement designed to support the skeletal system.

^*Steinke, S.L., J.B. Montgomery, and J.M. Barden. 2021. Accelerometry-based step count validation for horse movement analysis during stall confinement. Frontiers in Veterinary Science 8:681213.

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Equine Grazing Behavior Offers Clues For Forage Needs As Pastures Decline

As the growing season winds down or as drought sets in, horse owners must provide horses with an appropriate alternative forage to fulfill fiber requirements. In most cases, this involves the use of hay, though other products such as haylage or hay cubes are appropriate and sometimes fed.

The question that looms large for most owners is when to offer alternative forage. The pasture reveals a couple of important clues, namely growth rate and plant health.

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Owners will know when pasture growth slows as there will be less need for routine mowing and maintenance. Depending on stocking rate—that is, the number of horses on any given acreage—pasture might withstand a slowdown in growth rate and continued grazing, so long as more land is allotted per horse. A large, seven-acre paddock that comfortably sustained five horses in peak growing season might support three as pasture growth declines.

“Observation of grazing behavior might be a tipoff, too. If horses spend more time grazing, they are likely finding less to eat. In periods of lush growth, you might catch horses resting more often, as it is easier for them to satisfy their appetites and their need to graze,” said Dr. Kathleen Crandell, a nutritionist with Kentucky Equine Research (KER).

Plant health is a more obvious indicator. As autumn segues into winter or as rainfall decreases, pasture grasses often turn brown and unpalatable, at which time growth is almost assuredly arrested. Horses will snack on these remnants, but more nutritious forage should be offered.

“Owners ought to offer hay as soon as they feel horses are not consuming sufficient pasture to meet daily forage requirement, which is about 1.5-2 percent of body weight daily,” advised Crandell.

For a 15.2-hand, 1,100-pound horse, that would be 16.5-22 pounds of hay each day. Keep in mind, though, that this amount will likely satisfy the horse's complete forage requirement.

“If the horse is still nibbling away at pasture much of the day, it might need only a portion of this. If the horse leaves hay in favor of pasture, then too much hay is probably being fed at the time. Gauge requirement through consumption,” recommended Crandell.

To maintain weight, many horses, in combination with their forage, will be consuming a well-fortified concentrate feed that supplies all of the protein, vitamins, and minerals required for their well-being. Those that do not should be fed a vitamin and mineral supplement, such as Micro-Max, developed by Kentucky Equine Research and available in the U.S. and other regions. Micro-Max supplies minerals that have been chelated or proteinated, which increases their digestibility and allows horses to derive maximum benefit from them.

One vitamin that is particularly deficient in diets composed of preserved forages such as hay is vitamin E, an important antioxidant in the horse's immune arsenal. The most effective source of supplemental vitamin E is d-alpha-tocopherol or natural vitamin E. Nano-E is a natural-source vitamin E supplement that possesses a unique delivery action, nanodispersion, which allows the vitamin to hit target tissues more quickly than other vitamin E supplements. Nano-E is available worldwide.

Don't know where to begin with supplementation? Complete a simple questionnaire and start the consultation process.

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