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Study: Colic The Primary Cause Of Death For Geriatric Horses In Retirement Centers

The primary causes of death among horses at a retirement facility include colic, lameness, neurological deficits, and the cumulative effects of old age, according to new research from the Netherlands.

Using records from a private equine retirement center gathered over an eight-year period, researchers aimed to pinpoint the most common causes of death in aged horses and, more specifically, to determine the effects of pituitary pars intermedia dysfunction (PPID) on mortality.^*

For this study, any horse 15 years of age or older was considered geriatric.

After an exhaustive review of records, researchers created fourteen categories for the cause of death: colic, lameness excluding laminitis, laminitis, down in the field, neurological deficit, sudden death, acute illness, chronic weight loss, tumor, fracture or trauma, behavior, financial, and old age. A “financial” cause of death indicated euthanasia occurred because of an owner's inability to pay for care, and “old age” designated a horse with multiple problems that cumulatively decreased welfare and whose life ended by planned euthanasia.

All horses at the facility were overseen by professional horsemen and veterinarians and were provided with routine care. Testing for PPID occurred if there were any clinical indications of the disease (cresty neck, history of laminitis, chronic infections, weight loss).

Of the 194 horses that resided at the facility, 80 geriatric horses died during the eight-year period. Twelve were between the ages of 15 and 19 years old, 25 were between 21 and 25 years old, 32 were between 25 and 30 years old, and 11 were 31 or older. The average age of those horses that died was 26 years old. All were euthanized or died of natural causes.

The most common cause of death among this population of geriatric horses was colic (20% of cases) followed by old age (15%) and lameness that did not involve laminitis (12%). Neurologic problems and an inability to rise after lying down rounded out the top five causes of death.

“For those of us that live and breathe horses, that spend time each day with horses, that study horses, these causes of death come as no surprise,” said Catherine Whitehouse, M.S., a nutritionist with Kentucky Equine Research. “The interesting aspect of this study is that this data was all mined from the records of horses housed at a single facility under similar management conditions. Because of this, there was less variation in care than there would have been if horses had been managed at multiple farms.”

With regard to PPID, of the 194 horses that resided at the facility, 125 (63%) were tested at least once for PPID. During the eight-year-study period, 62 horses of the 125 tested died, and 47 of those 62 (76%) had tested positive for PPID at an average age of 27 years old.

According to the study, horses were maintained on a diet of free-choice haylage with and were offered supplemental feed if necessary. The teeth of all horses were examined regularly and those with missing or problematic teeth were given mashes when necessary. Weight was monitored monthly using scales. “The horses at this facility appeared to be given top-flight care, especially when it came to provision of adequate feed, dental care, and regular deworming, all of which is important when it comes to lifespan,” Whitehouse said. “Old horses sometimes require more management, but the extra investment may pay off in added years at the end of a life.”

Aged horses often benefit from targeted supplementation. High-quality joint supplements can help ease the discomfort associated with the effects of a lifetime of service, and a research-proven hindgut buffer, like EquiShure, can help stabilize the pH of the hindgut so microbes can efficiently ferment forages.

^*Van Proosdij, R., and S. Frietman. 2021. Retrospective analysis of cause-of-death at an equine retirement center in the Netherlands over an eight-year period. Journal of Equine Veterinary Science 110:103824.

Reprinted courtesy of Kentucky Equine Research. Visit ker.com for the latest in equine nutrition and management, and subscribe to Equinews to receive these articles directly.

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The Skinny On Beet Pulp As An Equine Feed

Fifty years ago, many knowledgeable horsemen would find it difficult to identify beet pulp or its potential value as a feedstuff for horses. Though its usefulness is now cemented among horse owners, beet pulp can still cause some confusion. Dr. Kathleen Crandell, a nutritionist for Kentucky Equine Research, answers eight questions about beet pulp and its role in equine nutrition.

In what types of feeds was beet pulp first used?

Sugar beet pulp first found a use in commercial horse feeds in the racehorse products as a low-dust feedstuff because it was mixed with lots of molasses and felt moist. This proved beneficial for the respiratory tract and was thought to be somehow beneficial in preventing bleeding, though this notion was quickly abandoned.

Beet pulp was also integrated into senior feeds because of the need for a high-fiber feedstuff that could be ground and incorporated into a pellet. The new generation of high-fiber, low-starch feeds that emerged in the late 1990s was an obvious end-use for such an excellent fiber source. Now, beet pulp is prevalent in feeds designed for all classes of horses.

What are the differences between beet pulp and cereal grains as energy sources?

Horses derive the majority of the energy (calories) in cereal grains from the enzymatic digestion of starch that is absorbed in the bloodstream in the form of glucose. On the other hand, horses derive the majority of the energy in beet pulp from the microbial fermentation of the fiber content, which is absorbed as volatile fatty acids, also known as short-chain fatty acids.

What are the advantages of feeding beet pulp as part of a diet?

Compared to other fiber sources like hay, beet pulp has much more digestible fiber. For example, the digestible fiber in hay is around 40 percent, while beet pulp has closer to 80 percent digestible fiber. The more digestible the fiber, the more calories that feedstuff provides the horse.

Further, beet pulp mixes well into a textured feed and can be pelleted easily. Plus, soaking beet pulp is a way to get more water into the horse.

How does beet pulp stack up to hay as a source of fiber?

The type of fiber found in beet pulp, considered “rapidly fermentable fiber,” is much more readily fermented by the microbes in the hindgut than the fiber in hay or typical forage sources. Hay consists mostly of cellulose, hemicellulose, and lignin. While lignin is completely indigestible, cellulose and hemicellulose vary in digestibility depending on the maturity of the plant.

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Beet pulp provides energy, but does it add appreciable amounts of other nutrients?

Beet pulp has higher amounts of calcium than grains, about the level found in typical commercial concentrates. In addition, beet pulp is comparatively high in iron.

Should beet pulp be fed soaked or unsoaked when fed by itself or as part of home-mixed concentrate?

If feeding beet pulp shreds, they can be fed dry, especially if mixed with other feedstuffs. Free-choice water availability is important if feeding dry beet pulp. Pelleted beet pulp, however, should not be fed dry because it may increase the likelihood of choke. Horses prefer to consume beet pulp shreds soaked rather than dry shreds, probably because it softens their texture. My preference is to feed beet pulp soaked.

Further, one of the advantages of feeding soaked beet pulp is that it is a way to sneak a bit of water into the diet, especially in the winter when water consumption may be down. The Europeans have come up with a method of micronizing and then flaking the pulp so that it soaks quickly, in less than 10 minutes.

Are there any special uses for beet pulp?

Soaked beet pulp is a useful vehicle for holding larger amounts of oil, which is often recommended as a way to get more calories in the horse.

It was thought for a while that soaked beet pulp could help to push sand out of the digestive tract, but research found it ineffective in prevention of sand colic.

Is beet pulp use in the U.S. different than in other areas of the world?

Beet pulp has worked its way into quite a number of commercial feeds in the U.S. Many horse owners feed soaked beet pulp in addition their regular feed.

As the history of beet pulp would suggest, its use is more longstanding in areas such as England, Northern Europe, and Russia, where much sugar beet is cultivated. Because of the climate needed for sugar beet cultivation, South America had very limited sugar beet production, as was the case in Australia and Africa. However, cultivation is expanding to newer areas because of a variety that can be grown in the warmer climates as a winter crop, instead of a summer crop as it is in more temperate climates. Where beet pulp is not grown, it may be imported and therefore rather expensive.

Are you interested in how beet pulp became a feedstuff for horses? Learn more at Beet Pulp in Horse Feeds: A Brief History.

Could beet pulp be an appropriate feedstuff for your horse? Contact a Kentucky Equine Research nutrition advisor today.

Article reprinted courtesy of Kentucky Equine Research (KER). Visit equinews.com for the latest in equine nutrition and management, and subscribe to The Weekly Feed to receive these articles directly (equinews.com/newsletters).

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Should Exercising Horses Receive Supplemental Antioxidants?

Among many other benefits, regular exercise enhances antioxidant defenses in horses. During exercise, aerobic cells generate reactive oxygen species (ROS), which are unstable atoms or molecules produced during normal cell metabolism. An overabundance of ROS can crush antioxidant defenses, leading to detrimental effects on muscle function. In an effort to quell the damage caused by ROS, researchers set out to determine the effect of N-acetyl cysteine and coenzyme Q10 supplementation on ROS in skeletal muscle of exercising horses.

Seven Thoroughbreds were used in the study, all engaged in the same training program: galloped 1.5 miles on the track three days a week, and walked and trotted on an automated exerciser three days a week. Horses were allowed access to pasture four days each week, three hours on exercise days and eight hours on their rest day. Horses were fed timothy hay ad libitum and a performance concentrate based on weight three times a day. Horses were supplemented daily with 10 g of N-acetyl cysteine and 1.6 g of coenzyme Q10.

Thirty days after supplementation began, horses performed an exercise test that consisted of a half-mile breeze on a racetrack at top speed. A second exercise test was performed at 60 days, with the same experienced rider instructed to replicate the speed from the earlier exercise test.

Muscle samples were taken the day before both exercise tests and one hour after each exercise test. Concentrations of antioxidants, cysteine, and ROS were measured. Blood samples were pulled prior to the exercise test and 10 minutes, one hour, and four hours after the exercise test.

The researchers concluded that supplementation of exercising Thoroughbred horses with N-acetyl cysteine and coenzyme Q10 for 30 days influenced antioxidant status without detrimental effects on performance.

Athletic performance and muscle diseases such as myofibrillar myopathy, equine motor neuron disease, and vitamin E responsive myopathy are affected by antioxidant status. Kentucky Equine Research has formulated multiple antioxidants designed for equine athletes, notably MFM Pellet, a palatable source of N-acetyl cysteine; Nano-E, a natural-source, water-soluble vitamin E supplement, and Nano-Q10, a highly bioavailable form of coenzyme Q10.

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“We have already seen the impact of this research, and horses diagnosed with myofibrillar myopathy are now being supplemented with MFM Pellet,” explained Marisa Henry, the lead author on the research paper. “We have heard glowing reviews from the owners of horses who have seen much improvement with MFM Pellet!”

This new study represents another chapter in the longstanding association between Kentucky Equine Research, Stephanie Valberg, D.V.M., Ph.D., and her colleagues, including Henry. Valberg is the director of the Equine Neuromuscular Diagnostic Laboratory and Mary Anne McPhail Dressage Chair in Equine Sports Medicine at Michigan State University, Department of Large Animal Clinical Sciences.

^*Henry, M.L., D. Velez-Irizarry, J.D. Pagan, L. Sordillo, J. Gandy, and S.J. Valberg. 2021. The impact of N-acetyl cysteine and coenzyme Q10 supplementation on skeletal muscle antioxidants and proteome in fit Thoroughbred horses. Antioxidants 10:1739.

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Do Fatty Acids Benefit Foals In Utero?

Omega-3 fatty acids have many favorable health effects on horses, including joint, respiratory, and reproductive benefits. Supplementing pregnant mares with omega-3s late in gestation has advantages for their developing foals. However, not all types of omega-3 supplements fed to mares have the same effectiveness.

The two major sources of omega-3 fatty acids for horses are:

Plant-derived short-chain omega-3 fatty acids, primarily alpha linoleic acid (ALA). High levels of ALA are found in flaxseed, canola oil, and other feedstuffs, but ALA must be converted by the horse to long-chain omega-3 fatty acids, including DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) for optimal use by horses.

Marine-derived omega-3s rich in the specific omega-3 fatty acids DHA and EPA. Providing a direct source of these omega-3 fatty acids may be preferred, as the conversion of ALA to long-chain fatty acids is limited in horses.

No study has determined if the omega-3s offered in a mare's diet actually reaches her unborn foal.

To fill this knowledge gap, researchers recently designed a study to measure omega-3 fatty acid levels in foals from supplemented mares. Three diets that provided a similar total amount of omega-3 fatty acids from two different sources were used. The first was a control diet, the second was the control diet plus a commercial flaxseed supplement, and the third was the control diet with a commercial marine-derived omega-3 supplement.

When mares were offered each of these supplements during the last 30 days of gestation, only marine-derived supplementation resulted in a significant increase in DHA levels in foals.

The DHA measured in blood samples from foals born to mares offered only the control diet was 0.6 g/100 g of lipid (fat). In the foals from mares supplemented with the marine-derived omega-3, the DHA was significantly higher at 1.9 g/100 g lipid.

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“No difference in foal DHA blood levels was observed between the control and flaxseed diets, which means these results support the recommendation to provide a direct source of DHA and EPA due to the low conversion rate of ALA to DHA,” relayed Catherine Whitehouse, M.S., a nutritionist for Kentucky Equine Research.

Even though mares were supplemented during the first five days after foaling and foals were nursing those mares, DHA levels declined rapidly. By day five, DHA levels were similar across all diets. On day 30, which was 25 days after the mares were no longer supplemented, the DHA blood level of the foals was only 0.1 g/100 g lipid.

“Continuing to supplement mares throughout nursing until weaning may help maintain higher DHA levels in foals after foaling, providing long-term advantages to growth and development,” suggested Whitehouse.

EO-3, a marine-derived omega-3 supplement developed by Kentucky Equine Research, provides research-proven levels of DHA and EPA, can be top-dressed onto feed easily.

*Snyder, J. N. Shost, R. Miller, K. Fikes, R. Smith, B. Corl, A. Wagner, I. Girard, and J. Suagee-Bedore 2021. Late gestation supplementation of long-chain fatty acids increases foal docosahexaenoic acid concentrations at birth. Journal of Equine Veterinary Science 100:103522.

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