Abdominal Surgery Poses Greatest Risk Of Surgical Site Infection

As with human surgery, there is always a potential for infection during equine surgery, Drs. Kelmer, Paz, Tatz, Dahan, Bdolah-abram and Oreff reviewed 198 post-operative complications related to surgery procedures on 167 horses at the Koret School of Veterinary Medicine in Israel over a 15-month period.

The study reviewed  40 percent abdominal surgeries, 30 percent orthopedic surgery and the rest were general surgeries that had a 9 to 20 percent chance of developing a surgical site infection. The incidence of infection was 16.7 percent during the study period.

The study team noted that post-operative surgical site infections created difficulties with recovery, increased the length of stay in the hospital, increased client coats sand delayed return to work. It addition, surgical site infections caused an increase in equine morbidity and mortality.

Of all the surgeries performed, abdominal procedures had the highest risk of infection with 28 percent. This may be because of the length of the incision or the weight of the intestines on the incisions.

The scientists identified the following as factors that increase the risk for a surgical site infection:

  • Type of surgery.
  • Having a repeat surgery in less than 6 months in the same area or in an area near the original incision. Abdominal procedures are particularly at risk.
  • Weight of the horse. Heavier horses have more weight resting on the incision line in their abdomen.
  • Gender. In the study, only 2.3 percent of stallions developed infections, compared to 16.1 percent of geldings and 24.3 percent of mares; 50 percent of pregnant mares had surgical site complications.
  • Recovery from anesthesia. A horse that has a hard time recovering from anesthesia may increase his risk of infection development by four times.

Abdominal procedure infection rate ranges from 7 to 37 percent; arthroscopic surgery infection rate was less than 1 percent. Overall infection frequency in orthopedic procedures was around 10 percent.

The team found that other factors may amplify infection risk. These include time of day and season when the surgery takes place; the surgeon; and a horse's breed and age. They also note that as this study looked at cases between 2011 and 2013, surgical techniques, bacterial resistance and bacterial populations have changes, so additional studies are needed.

Read more at EquiManagement.

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Ancient Remedy Shows Promise As Antimicrobial

Antimicrobial resistance is of great concern to those involved in equine health; multidrug resistance is posing a massive challenge to managing microbial infections. Infections that cause biofilms are even harder to resolve; it's estimated that biofilms require 100 to 1,000 times higher antibiotic concentrations that non-biofilm-producing bacterial infections.

Drs. Jessica Furner-Pardoe, Blessing Anonye, Ricky Cain, John Moat, Catherine Ortori, Christina Lee, David Barrett, Christophe Corre and Freya Harrison investigated the efficacy of a 1,000-year-old herbal remedy found in a 10th century Old English medical compendium. The remedy, called Bald's eye salve, consists of onion, garlic, dry white wine and bovine bile salts.

The team found that this topical remedy was useful against specific soft tissue wound pathogens. To create the salve, the scientists chopped and crushed the onions and garlic, and brewed them with wine and bile salts. They then stored the liquid in sterilized glass bottles at around 39 degrees Fahrenheit in the dark for nine days. The ingredients were then strained and centrifuged to obtain a liquid that was filtered and stored in the same sterilized glass bottles.

When tested against wounds that contained MRSA, Bald's eye salve obtained a 90 percent bacterial kill and was comparable to vancomycin. The medication didn't cause damage to either human cells in the laboratory or to mice.

The combination of all the ingredients is what makes it effective against biofilms. If any ingredient is left out, the preparation is not effective.

Read the full article here.

Read more at EquiManagement.

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NZ Horse Diagnosed With Novel Papilloma Virus

A 10-year-old Warmblood gelding in New Zealand was referred to a veterinary clinic with two masses on his left fetlock. The masses were each over an inch in diameter and had hard, rough surfaces. They grew rapidly in the three weeks since the horse's owner had discovered them. A piece of one of the masses was sent for microscopic evaluation and Drs. John Munday, Michael Hardcastle and Melissa Sim determined that a novel papillomavirus caused the lesions.

Papillomaviruses are double-stranded DNA viruses that tend to be host specific. There are nine equine papillomaviruses that have been sequenced; the first to be sequenced was Equus caballus type 1 (EcPV1), which causes papillomas in horses.

The masses the gelding had were most similar to EcPV1, but they didn't present in the same way: EcPV1 generally causes small masses around the face. Veterinarians treated the masses with imiquimod ad the lesions resolved in 14 weeks.

The study team noted that papillomas only develop when a host is infected by a papillomavirus for the first time, which is why warts (papillomas) typically develop in young horses. This is an additional indication that the virus that caused the lesions in the older horse is new.

Read the full study here.

Read more at HorseTalk.

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Two Horses Infected With Piegeon Fever In Washington State

Two horses have tested positive for pigeon fever in Clark County, WA. Both horses are housed at the same farm. Equids, cattle, sheep, goats, buffalo and camelids can contract West Nile, as can people in rare instances. The disease can be highly contagious if it is not managed properly; there is no licensed vaccine available.

Pigeon fever is caused by a bacteria that can persist in soil for months; in horses it is primarily spread from through open wounds or by flies. Pigeon fever most commonly presents as external abscesses on the chest or abdomen, though internal abscesses can also occur. This disease is typically present in hot, dry Western climates, but has spread to states such as Florida and Kentucky.

Read more at the Equine Disease Communication Center.

Reade the AAEP Infectious Disease Guidelines here.

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