Kentucky Commission: Hidden Scroll Was State’s First Epistaxis Case Since 24-Hour Lasix Ban

Hidden Scroll, who pulled up after crossing the wire seventh in Saturday's Grade 3 Commonwealth Stakes, is the first case of epistaxis from exercise-induced pulmonary hemorrhage (EIPH) in Kentucky since the state implemented new furosemide administration rules in 2020. The Brad Cox trainee went off at odds of 2-1 for his first start without the race day medication, which is commonly known by its trade name of Lasix or Salix.

Kentucky began a partial phaseout of race day furosemide last year, beginning with 2-year-old races and expanding to include stakes races this year. The drug may now be given no closer than 24 hours before post time in those contests.

Dr. Bruce Howard, equine medical director for the Kentucky Horse Racing Commission, confirmed that Hidden Scroll's case of epistaxis (visible bleeding from the nostrils) due to EIPH was the first on record since the new rules were implemented. EIPH can occur without visible bleeding from the nostrils and is often detectable only on endoscopic examination; more severe incidents may result in epistaxis.

A frustrated Joe Orseno, who trains multiple graded stakes winner Imprimis, told media immediately after the horse's runner-up effort in the G2 Shakertown that he believed his horse also suffered from epistaxis due to EIPH. Orseno said he could see blood on the horse's nose at the finish, where he was just edged by Bound for Nowhere.

“You're not allowed to run on Lasix anymore,” said Orseno. “They're taking the best horses in the country and they're penalizing them. My horse bled today, visibly. Blood coming out of his nose. How is that good for the public's perception of Lasix? Somebody needs to answer that question. It's not fair to take a horse like this and make 'em bleed. It's just not fair. I wish you'd print every word of that, because it's total bullshit.

“My horse didn't have to bleed. Let him run on Lasix … I care about my horse and his physical condition.”

Orseno pointed out that a bleeding event from EIPH can knock a horse off its training schedule.

“I was supposed to run him in two months, now it's going to be four,” he said. “So I've got to tell the owners, forget the Jaipur, now maybe Saratoga, maybe not, because who knows. I don't know. You never know the damage it does to horses.”

The full interview, courtesy of the Kentucky Horsemen's Benevolent and Protective Association's Jennie Rees, is available here, following comments from Bound for Nowhere trainer Wesley Ward:

Howard said that besides Hidden Scroll, there was one other incident on Saturday's card related to blood on a horse's nose, but it wasn't a result of EIPH.

“I think the other one which might have been commented on was a horse who broke through the starting gate before the start,” said Howard. “It was examined and reloaded, and ran its race. Post-race, there was a small amount of blood noted in a nostril. The horse was examined in the test barn and a small abrasion or laceration was noted. The private veterinarian came and scoped the horse and there was no bleeding noted in the lower airways.”

Imprimis broke through the starting gate before the start of the Shakertown.

Kentucky's commission voted unanimously for the partial furosemide phaseout in December 2019 and racetracks implemented house rules preventing the administration of furosemide less than 24 hours before a race for 2-year-olds beginning in spring 2020, as a stopgap until the new rule worked its way through legislative approval and became law. The Kentucky HBPA took the tracks and commission to court over the house rules and commission regulation changes. A judge ruled in favor of the tracks and commission in November 2020.

Kentucky does keep records of epistaxis events, and is also participating in a multi-jurisdiction study to administer scopes post-race on horses subject to the 24-hour furosemide rule. The academic study, led by Washington State University, will compare scope results from jurisdictions with a variety of furosemide administration times. Data collection is ongoing and the university is not expected to release results until analysis is complete. Howard was unable to comment on the data collected from Kentucky.

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Standing Equine PET Now In Use At UC Davis

UC Davis has welcomed the latest standing equine PET scanner, the MILEPET, into clinical use, less than six years after performing the world's first PET scan on a horse.

Thanks to funding support from the UC Davis Center for Equine Health and the Stronach Group, the UC Davis veterinary hospital recently installed the most recent MILEPET. After the installation of the first scanner at Santa Anita Park racetrack, a second scanner was set up on the East Coast at the University of Pennsylvania. This newest instrument at UC Davis will provide the most innovative equine imaging technique using only standing sedation to the Northern California horse population.

Since the first equine PET scan was performed at UC Davis in 2015, there have been many other “firsts” as the team, led by Dr. Mathieu Spriet, worked to develop the use of the technique to improve detection of injuries in equine limbs. The   s were performed two years ago, removing the need for horses to undergo general anesthesia during imaging. Subsequently, our group validated the first scanner designed specifically to image horses prior to its installation at Santa Anita in Southern California. This scanner has now been used for over 200 studies at the racetrack, contributing to reducing the number of catastrophic injuries in racehorses.

For the past five years, the UC Davis veterinary hospital's robust equine clinical program has imaged over 100 horses, but until recently, all of these scans were performed with the piPET, a scanner originally developed to image the human brain. This program accomplished several milestones in the development of equine PET, establishing applications not only for racehorse safety, but also for diagnosis of bone and soft tissue injuries in sport horses and improved understanding of laminitis. The clinical use of the technique was limited due to the requirement to anesthetize horses, which increases costs and risks associated with the procedure.

The initial clinical case utilizing the new scanner at the UC Davis veterinary hospital was another first, a mule named Jool. She was the first patient included in a clinical trial aimed at combining standing PET with standing MRI to provide the most advanced imaging for foot lameness in horses (or mules).

In addition, a second standing PET study is underway, aimed at assessing the progression of laminitis. Laminitis is an extremely debilitating disease that can unfortunately be fatal. Laminitic patients require long-term, careful hoof care performed by an experienced farrier. UC Davis veterinary hospital farrier Shane Westman has a long list of these challenging patients. In order to manage the trimming and shoeing optimally, Westman relies on imaging techniques. In a pilot study performed on laminitic cases at UC Davis, PET demonstrated its value in precisely assessing the involvement of the soft tissues of the foot with laminitis. As PET now becomes available using simple sedation, it simplifies the use of the technique and allows for repeated scans every time a patient comes for shoeing and trimming.

In addition to these two specific clinical research studies, standing PET is now available to any equine patient in Northern California. Standing PET can image any area of the limb from the foot to the carpus (knee) or tarsus (hock).

The racehorse population of Golden Gate Fields racetrack will also benefit from the new PET scanner. As the technique has quickly gained in popularity at Santa Anita Park, a few Northern California racehorses have traveled south to be imaged with PET. Now these horses won't need to travel so far. In addition to being in operation at UC Davis, the MILEPET scanner will soon be transported on a weekly basis to image horses at the equine hospital at Golden Gate Fields.

Dr. Spriet was very enthusiastic about these latest developments in the UC Davis equine PET program, “The standing PET scanner will allow us to offer this cutting-edge modality to more cases than we could before. Repeating scans on the same patient will help us optimize treatment and rehabilitation for better outcomes.”

“Through support from our donors and endowments, we have been able to support the equine PET program at UC Davis since 2016 by providing both research and equipment support,” said Dr. Carrie Finno, director of the UC Davis Center for Equine Health. “It is incredibly rewarding to see this technology now being used to prevent catastrophic injuries in racehorses across California.”

More horses, and mules, will be scanned in the near future!

Read more here.

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Study: More Than Half Of Eventers Coming Back From Cross Country With Mouth Sores

Concern over oral injuries from bit use has equine advocates questioning horse welfare in many disciplines, including harness racing and eventing. A Finnish study has shown that horses competing in eventing are at greater risk of developing mouth sores after the cross-country phase of competition.

Drs. Kati Tuomola, Nina Mäki-Kihniä, Anna Valros, Anna Mykkänen and Minna Kujala-Wirth looked into the mouths of 208 event horses at the conclusion of the cross-country phase at eight competitions. They found that 52 percent of the horses had acute oral lesions; of these, 22 percent were mild, 26 percent were moderate and 4 percent of the horses had severe lesions. The team found that oral bruising was more common than open wounds.

Researchers also found that horses competing in particularly thin or thick bits were at greater risk of oral lesions, likely due to mechanics and fit. Additionally, Warmbloods and cold-blooded horses were at higher risk of having oral lesions than ponies, and mares were more likely to have serious lesions than geldings.

The researchers advise that bit monitoring be implemented by horse owners and by competition management to ensure equine welfare. There was no association between lesions and competition placement during the study; high-performing horses are still at risk of oral lesions.

Read the article here.

Read more at HorseTalk.

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Inhaled Human Medication Helpful For Asthmatic Horses

The British Equine Veterinary Association (BEVA) has reported that inhaled ciclesonide can assist in controlling severe asthma in horses. Horses with severe asthma often cough, have a runny nose and have difficulty forcing air into their lungs.

Corticosteroids have been shown to calm inflammation in the respiratory tract. These medications can be administered multiple ways, but inhaled therapy is considered ideal as it gets the drug directly into the lungs. Ciclesonide is used in human medicine and has been shown to be effective in horses that become asthmatic when exposed to certain conditions like moldy hay. The drug had not been studied in the field.

Researchers used 220 severely asthmatic horses from 24 clinics in Germany, France and Switzerland for a study to test inhaled ciclesonide efficacy. The horses either received an inhalation solution containing ciclesonide or a placebo inhalation.

To test their hypothesis, the horses were given ciclesonide through an equine inhaler at eight actuations twice daily and then 12 actuations once daily for five days. The horses receiving the placebo received the same number of treatments, but they did not contain ciclesonide.

The study team found that 73 percent of the horses receiving ciclesonide showed improvement in their asthma after the 10-day study. Horses with more severe asthma showed the most improvement. Horse owners reported an improved quality of life in nearly 70 percent of the ciclesonide-treated horses.

Read the full article here.

Read more at EquiManagement.

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