Updated: Four Barns At Laurel Under Quarantine Due To Equine Herpesvirus

Four barns at Laurel Park — Barns 1, 4, 10, and 11 — have been placed under quarantine after one horse developed neurological symptoms over the weekend and subsequently tested positive for equine herpesvirus.

According to a video conference call held Tuesday afternoon, one horse developed neurologic symptoms over the weekend and was quickly removed to the Marion duPont Scott Equine Medical Center in Leesburg, Va., where the horse is responding well to treatment. Test results later indicated the horse was positive for the “wild type” strain of EHV-1.

There are two closely related strains of EHV-1 that may be indicated in testing, and they're commonly called the “wild type” and the “neuropathogenic type.” Both can cause neurological symptoms and are handled basically the same way by animal health officials.

Read more about EHV-1 in this Paulick Report explainer from 2016.

Contact tracing on the horse later revealed it had potential exposures in the now-quarantined barns. Horses from those barns were not permitted to train Tuesday, but track management is working on a plan to allow them to train Wednesday morning. Those horses will not be permitted to gate school, and Maryland's equine welfare and medical director Dr. Libby Daniel indicated they would likely not be permitted to race.

The initial quarantine is expected to last 14 days, but a new positive will restart the quarantine length for the barn in which the new case is found. The 14-day period started March 8.

Dr. Michael Odian, Maryland state veterinarian, and Steve Koch, senior vice president of racing operations at The Stronach Group, emphasized that diligence by all personnel will be key to minimizing disease spread and getting the quarantine orders lifted as scheduled.

“The trick is we have to be super diligent throughout that 14 days, make sure there is no cross contamination or exposures that cause further barns to be quarantined,” said Koch. “All horses need to be asymptomatic during that period.”

Horses can continue to enter Laurel during this time, but will not be permitted to leave. The same rules will apply at Pimlico, except that horses who leave Pimlico to run at Laurel may return to Pimlico. The two facilities are being treated as one property for the purposes of the outbreak.

Horsemen are asked to take horses' temperatures twice daily and monitor them for signs of the disease. Equine herpesvirus is a highly transmissible respiratory illness which can spread through nasal discharge or aerosol droplets. It can also be spread passively on surfaces such as human hands, shared grooming tools, and tack.

Horses that are symptomatic (those that have a fever of 102 degrees or higher or those showing neurological signs) should be tested as soon as possible. Crews have cleaned out Barn 29 on the Laurel backstretch and horsemen are encouraged to remove horses from their shedrows at the first sign of potential illness and take them to Barn 29 to reduce the amount of time the virus could be passed to horses in neighboring stalls. Horses should be tested for the virus only if they show symptoms, and will be tested twice — once when they become symptomatic, and once 72 hours later. The goal of the second test is to catch horses who may show symptoms before actually shedding enough of the virus to be picked up on the first test.

Staff working in quarantine barns should not go from quarantined areas to non-quarantined areas. They should save their work in quarantine barns for the end of the day, and leave the facility after working in those barns. Staff are encouraged to keep a change of shoes to be used only in quarantined barns, or to use pull-on rubber galoshes over existing boots. Ideally, staff should also wear coveralls over their clothes when working in a quarantined area. All equipment should be wiped down with disinfectant at the end of each work day to prevent disease transmission.

EHV-1 outbreaks have been in the headlines in the equestrian world in recent weeks. A large outbreak in Europe has frozen international competitions there, and an outbreak connected to the World Equestrian Center in Ocala, Fla., saw its third suspected case over the weekend after two horses tested positive. All three horses exhibited high fevers, one nine days after leaving the Center. Odian confirmed the strain of the virus at Laurel is not the same as the strain in the European outbreak, and said he did not believe it was the same strain connected with recent positives in Florida or one in Pennsylvania.

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EHV-1 Outbreak Update: Kentucky Requires Horses Coming From Ocala Have Health Certs Within 72 Hours

The following update and guidance were released to event and facility managers by E.S. “Rusty” Ford, equine operations consultant for Kentucky's Office of the State Veterinarian on March 8: 

OVERVIEW

In the past seven days we have learned of multiple occurrences of EHV-1 impacting equine events throughout the world.  Additionally, as we are coming to the time of year that we historically see an increase in movement of equine exhibition and racing stock into Kentucky, I want to remind all associated parties that mitigating risk of disease introduction is a shared responsibility that requires commitment from each individual exhibitor, trainer, event managers, facility operators, veterinarians, and animal health officials. Facility managers and the managers of shows/exhibitions planned to be held in Kentucky should immediately review their biosecurity practices and if needed elevate their biosecurity plan to minimize opportunity of horses having direct or indirect contact with one another. Indirect contact would include common water and feed sources as well as shared equipment and congregating in common areas. The goal of a biosecurity plan is to prevent the transmission of infectious agents among individuals and the components of a successful program will include cooperation of management, facility layout, decontamination, and when applicable immunization. Each of these factors directly affects the success or failure of the program.

Copies of the American Association of Equine Practitioners biosecurity guidelines can be downloaded at https://aaep.org/site-search?search=biosecurity or the Equine Disease Communication Centers website www.equinediseasecc.org. The documents provide good general guidance of practices that should be routinely implemented, and we encourage show managers to share these directions with all exhibitors. Additionally, our office is happy to assist facilities, show management and event veterinarians in evaluating their individual plans and when a need is identified, assist in adopting and implementing a defined plan.

FLORIDA STATUS

I did earlier today speak with the Florida State Veterinarian overseeing the EHV-1 investigation and management of the disease incident in Ocala, Fla. As of today, there continues to be a single barn on the Ocala facility with EHV-1 cases confirmed by diagnostic testing. The barn remains under quarantine and activity on the premises is being monitored by animal health officials.  Equine presenting with evidence or suspicion of illness are being isolated and tested.

FLORIDA (Marion County) > KENTUCKY MOVEMENT

We appreciate the proactive action taken by the Florida Department of Agriculture to mitigate further transmission of EHV-1. With the epidemiological investigation still in its early stages, the status of potentially exposed horses unknown, and the potential risk of fomite (human) transmission to other facilities during the days preceding the diagnosis, Dr. Flynn and I both feel we are justified in stipulating that in addition to our normal entry requirements, horses destined to Kentucky from the Ocala area (identified as Marion County) be examined and a certificate of veterinary inspection (CVI) issued during the 72-hour period preceding the horse's arrival at the KY destination.

The examination and issuance of the CVI should be performed by a veterinarian familiar with the individual horse and the environment from which it originates and with confidence the horse has not been recently exposed to a reportable disease.  We will continue to monitor the activity in Florida and plan to reevaluate the CVI 72-hour policy during the week ending Sunday, March 21.

European Union EHV1 Concerns: Available Testing Options for Importing Horses

Importation and Preplanning

We continue to gather and assess information describing multiple outbreaks of EHV-1 impacting equine events in several European countries. Reports published yesterday suggest there are now six countries with confirmed cases: Spain, Germany, Belgium, France, Sweden and a case in Qatar that is apparently linked to the European outbreak.

USDA announced this past Friday that horses importing through federal quarantine facilities can be sampled while completing quarantine will be allowed to be sampled with those samples sent by permit to a USDA approved laboratory for EHV1 testing by PCR.  To schedule and accomplish testing, horsemen should work with their importing broker/agent to arrange for the samples to be collected, submitted, and tested.

USDA has advised us that results of the testing will be reported and shared before the horse releases from quarantine and that a positive result will not delay release of the animals so long as there is no fever or other symptoms detected. Our horsemen need to preplan and insure they have suitable space available to isolate and quarantine any horse that is reported positive. After the horse(s) arrives in Kentucky, we will work with the farm and attending veterinarians to better understand as quickly as possible the individual animal's disease status and associated risk it may pose.

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EHV-1 Positive Horse In Pennsylvania Not Associated To European Outbreak 

On March 3, the Equine Disease Communication Center (EDCC) reported that one horse was euthanized after being admitted to the University of Pennsylvania's New Bolton Center with neurologic signs of Equine Herpes Myeloencephalopathy (EHV-1).

The horse, who lived in Pennsylvania, had no known affiliation with any international travel or competition, and is not considered to be associated in any way with the EHV-1 outbreak in Europe.

Veterinarians and horse owners in the United States are closely following the EHV-1 outbreak in Europe and remain vigilant in their efforts to prevent its spread to the States. EHV-1 is spread between horses from nasal discharge or aerosol droplets, as well as from touching contaminated surfaces.

There is no vaccine for the neurologic strain of equine herpesvirus; the fatality rate can reach 30 percent in horses that develop neurologic signs. A horse that recovers from the disease may retain neurologic deficits.

Read more at the EDCC.

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Six Tips To Prevent And Treat Equine Herpesvirus From Hagyard’s Dr. Nathan Slovis

Equine Herpesvirus (EHV-1) can cause respiratory disease, abortions and neurological disease. Transmission occurs via the respiratory system, with droplets of the virus being spread by mucus via snorting, coughing and human contact.

If you are in a high-risk area where there's a greater incidence of EHV-1 cases, the following tips may help ensure the horses in your care are protected from infection. These precautionary strategies come directly from Dr. Nathan Slovis, DACVIM, at Hagyard Equine Medical Institute. As an Internal Medicine Specialist and the Infectious Disease & Biosecurity Director, he has implemented the current Infectious Disease and Equine Emergency Response Programs at Hagyard.

Consider sharing these strategies with clients who have horses in high-risk areas.

  1. Start monitoring your horse's temperature twice daily. Even if your horse has not been exposed, start recording their temperature now to understand what their normal baseline temperature is. A horse's temperature will usually spike prior to shedding significant amounts of the virus, and typically anything greater than 101.5°F should be considered a fever. If a fever is noted, you should isolate the horse to the best of your ability until a veterinarian can assess. It is recommended that any horse with a fever have both a whole blood sample and nasal swab submitted for PCR assessment for EHV-1 and EHV-4.
  2. Limit exposure to any stressful situations that are not necessary. Examples include elective surgeries and other medical procedures. Minimizing stress will help protect the immune system so it can better fight off infection.
  3. If your horse requires the use of corticosteroids, either systemically or intraarticularly, consult your veterinarian to see if it is feasible to stop administration. The continued use of corticosteroids can suppress the immune system and could hinder their ability to effectively fight off an infection.
  4. Increase biosecurity measures since humans can inadvertently spread the infection on their hands, grooming equipment, etc. EHV-1 can survive on inanimate objects like halters, lead ropes, and tack, but is easy to kill on surfaces with disinfection. Therefore, these simple biosecurity measures can help stop the spread:
  • Wash or sanitize your hands between interacting with each horse.
  • Take care when filling water buckets and feed tubs – neither the hose nor the feed scoop should have contact with the bucket or tub.
  • Minimize the use of shared equipment, disinfecting tack (bits, bridles, etc.) between horses. Items like water buckets and feed tubs should not be shared.
  • There are a multitude of safe and effective disinfectants available. A few I recommend are a 1:4 ratio of bleach to water, or accelerated hydrogen peroxide-based disinfectants (like Rescue™) since they are safe for both human and animal use.
  1. Keep your horse up to date with their EHV vaccine schedule. If you horse has not been vaccinated against EHV three months prior to travelling into an area that has a high incidence of EHV, then I would recommend vaccinating your horse. If you are in a high-risk area, consult your veterinarian about the use of vaccines that have a high antigenic load for herpes virus so you can get a robust immune response. Remember, there is no vaccine on the market that can prevent the neurological form of EHV-1. The goal of vaccinating is to reduce the severity of clinical signs and reduce shedding of the EHV-1 virus if a horse does get sick.
    Some inactivated vaccines with the highest number of antigens for virus neutralization include Calvenza®, Pneumabort-K® and Prodigy®. Other vaccines like Rhinomune® are a modified live vaccine, and also have a high virus neutralization response.
  1. If your horse is exposed or gets sick, contact your veterinarian to see what course of action they recommend. As mentioned, diagnosis requires the detection of the virus from either whole blood or nasal swab samples via PCR testing. If you are in a barn with a horse that has EHV-1, the use of the antiviral drug valacyclovir may decrease virus shedding and may help your horse from acquiring the infection. Veterinarians have also discussed the use of lysine to theoretically reduce viral replication. Horses can be administered safely 12 grams orally once daily in their feed. This has not been proven to prevent neurological forms of EHV-1.

In the neurologic form of EHV-1, the virus interacts with the blood vessels that supply the spinal cord. This inflammation in the blood vessels can cause a stroke-like event (blood clot), resulting in decreased blood flow to that portion of the spinal cord. To potentially prevent this from happening, veterinarians may prescribe anticoagulants like aspirin and/or heparin to prevent this from happening if your horse becomes clinical.

To learn more about Equine Herpesvirus, Dr. Slovis recommends referring to the American Association of Equine Practitioners (AAEP) website for accurate information and resources.

Read more here.

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