Gabapentin: What Is It?

The news last week that leading trainer Saffie Joseph Jr. has been suspended for 15 days and fined $500 by the Pennsylvania Racing Commission—pending appeal—after one of his trainees tested positive for the substance gabapentin after winning a graded stake at Presque Isle Downs last September, led to a collective head scratch.

What exactly is gabapentin?

“It is a drug that is used as an anti-convulsant in people. It is also used for neurotrophic pain—in other words, pain originating from nerves,” said former California Horse Racing Board (CHRB) director, Rick Arthur. “For example, if you have shingles, they're likely to put you on gabapentin.”

According to the government run MedlinePlus website, gabapentin is commonly prescribed to help control certain types of seizures in people who have epilepsy, and works by decreasing abnormal excitement in the brain.

Common gabapentin medications include Horizant, Gralise, and Neurontin.

Its use in human medicine has increased as an alternative pain relief to highly addictive opioids, said Arthur. But “frankly, it is not very effective,” he added, of the orally administered drug. 

Gabapentin is a Class 3, penalty category B drug according to the Association of Racing Commissioners International, meaning it is deemed to have certain uses in racehorses.

Under the Horse Racing and Integrity Act's (HISA) impending anti-doping and medication control (ADMC) program, gabapentin is listed as a category B controlled substance. This means it is permitted for use in certain windows. 

When HISA's ADMC goes into effect on March 27, a first-time gabapentin positive comes with a possible 15-day suspension, a fine of up to $1,000, and automatic disqualification of the race-day results.

According to HISA's chief of science, Mary Scollay, because gabapentin is listed in the HISA technical document as an anti-convulsant, “I expect there could be successful legal argument that it's not an analgesic.”

So, for what kinds of issues can gabapentin be used to treat in horses?

“It was advocated about 10, 15 years ago as a way to treat navicular disease,” Arthur said. “But that kind of fell apart as it didn't work.”

It is also used to treat lameness in horses, “but more as a desperation move when they don't know what it is,” he added.

Because of its use as an anti-anxiety medication in humans, some say it has the same potential off-label use for horses, too.

Neither Southern California-based private veterinarian, Ryan Carpenter, nor current CHRB equine medical director, Jeff Blea, are aware of gabapentin being used as a calming agent in racehorses. Though Blea admitted that it could have that effect. 

According to the CHRB's stewards rulings webpage, there have been roughly 18 individual gabapentin positives in California since 2005.

“For the most part, they were normally cases where the humans associated with the horse were on gabapentin,” said Arthur, explaining how most cases were ruled instances of environmental contamination.

“We have no idea how the transfer occurs. We were suspicious that it was secondary contamination from someone urinating in the stall but we never confirmed that,” he said. 

In one instance, an off-track veterinarian had prescribed gabapentin to a dog that was brought to the barn, said Arthur. 

“We assumed it was from urine,” said Arthur, when asked about how the transfer was made. “Why someone would let a dog urinate in the stall I don't know. 

While the relationship between a person or an animal prescribed gabapentin and a positive finding in a horse is clear “in most cases,” said Arthur, “there were a number of instances where there was no explanation for it other than the horse being administered gabapentin.”

According to Arthur, if the reported finding shows gabapentin at nanograms in the low single digits, that is typically an indication of environmental contamination. 

“If it's up over 15, 20 nanograms, I would expect that to be an intentional administration,” said Arthur. “We had one case around 100 nanograms, which would be impossible to explain by accidental contamination.”

The Pennsylvania Racing Commission did not publish the amount at which gabapentin was found in Artie's Princess's (We Miss Artie) post-race sample. However, Joseph told the TDN last week that the horse tested positive at a level that should be considered below the recognized threshold level.

Joseph also told the TDN that the horse was tested 24 hours before the race by the same laboratory. “The horse was negative and was then positive the next day when no vet treated her. How is that possible? The proof is in the pudding,” said Joseph. 

According to Arthur, “you would not expect this drug to work for more than 12 to 24 hours in any sense as an analgesic or pain reducing medication.”

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Lucinda Finley Q&A: “Long Litigation Road Ahead” For HISA

The Congressional amendment to the Horseracing Integrity and Safety Act (HISA) at the end of last year–affording the Federal Trade Commission (FTC) more rule-making governance–has not yielded a pause on the legal maneuverings surrounding the law.

Already this year, the Fifth Circuit Court of Appeals denied a motion by the HISA Authority for that court to vacate its recent opinion that HISA is unconstitutional, and instead sent two different cases back down to the district court level.

In response, the Texas Racing Commission–which has so far barred the federal law from being enforced in its jurisdiction–said the action meant Texas tracks could once again beam their simulcasting signals out-of-state. Sam Houston, which is currently running, has so far refrained from taking that course due to the “” swirling around the matter.

At the end of January, the FTC published HISA's Anti-Doping and Medication Control (ADMC) rules on the Federal Register, initiating a 14-day public comment period. Should the FTC approve them, HISA has set a program implementation date of March 27.

All the while, two other HISA-related lawsuits are working their way through the courts–one currently before the Sixth Circuit Court of Appeals, and the other in the Texas Northern District Court, Amarillo Division.

To get a handle on where all this leaves HISA, the TDN once again spoke with constitutional law expert Lucinda Finley, Frank Raichle Professor of Trial and Appellate Advocacy, and director of Appellate Advocacy at the University of Buffalo Law School.

The following is heavily edited from a longer interview.

TDN: Can you give an overview of where all the latest legal actions that have come down since we last spoke leave HISA?

LF: No court has yet ruled on whether the newly amended HISA–which gives the FTC greater authority to accept, reject, or modify the HISA Authority's proposed rules–is constitutional or not. But the congressional amendments to HISA do put it on stronger legal footing on the single issue that the U.S. Court of Appeals for the Fifth Circuit addressed, the private delegation doctrine, or in non-legal parlance, whether HISA granted too much authority to make rules to a private body, instead of the FTC.

The congressional amendments make it clear that the FTC has at least as much regulatory authority as the Securities and Exchange Commission [SEC] does when it considers whether to adopt rules proposed by a private body. The SEC rule making structure has repeatedly been ruled constitutional by many federal courts.

But despite how the congressional amendment responds to the Fifth Circuit concerns about the previous version of the HISA statute, it is not surprising to me that the Fifth Circuit panel refused to consider whether to vacate their opinion or to rehear the case. It is standard appellate procedure for a federal appellate court, after they've initially ruled, to send things back to the district court. The district court will be the first one to determine whether the amendments that Congress recently made are sufficient to satisfy the concerns that the Fifth Circuit had.

The other thing that the Fifth Circuit did is to lift a stay or a suspension of an injunction that another district court had issued against enforcing HISA in Louisiana and West Virginia. So, HISA cannot legally enforce its rules in those two states. But what HISA can do is go back to that district court and argue that the recent congressional amendments have satisfied the constitutional concerns raised by the Fifth Circuit–therefore that the amendments make HISA constitutional–so they could ask that district court to remove its injunction against enforcing HISA in West Virginia and Louisiana.

How I interpret the recent Fifth Circuit decision not to vacate its November ruling and not to rehear its November decision is to simply say: Take your arguments back to the district courts, let the district courts consider those arguments in light of our November ruling and in light of the amended statute.

TDN: Do they go back to the same district court?

LF: No, they go back to the district courts in which each case originated. One of them goes back to a district judge who initially found HISA, even before Congress amended it, to be constitutional. The other case, the West Virginia and Louisiana case, goes back to a district judge who expressed grave concerns about HISA's constitutionality prior to amendment.

TDN: In the district courts, are the plaintiffs likely to challenge other provisions of HISA?

LF: Several of the cases challenging HISA do raise other constitutional challenges in their original complaints, and they can argue all those other challenges back in the district court. If they didn't raise them [before], they could possibly ask to amend their complaints to raise other constitutional challenges.

In cases against HISA filed around the country, some of them challenge the way members of the private Authority are appointed, arguing that because they are functioning like federal government officials, they should be appointed through the process the constitution and federal statutes lay out for appointing and removing federal officials.

Now, that argument could be affected by Congress's recent amendments.

Before HISA was amended, plaintiffs' main argument was it delegated too much governmental authority to the private Authority, thus the private Authority was really acting like a governmental agency. So, if the courts think the new congressional amendments now leave the FTC with greater final say over what the HISA rules are, a judge may be less likely to accept the challenges to how members of the private Authority and its board are appointed. Again, to compare the HISA structure to the SEC, the way that members of the private body–known as FINRA–that proposes rules to the SEC are appointed has been upheld.

There are also cases bringing constitutional challenges to the private Authority's investigatory and enforcement powers. They claim that giving so much authority for investigating and punishing violations to a non-governmental body violates due process of law. No court has yet decided that argument.

In my opinion, that constitutional argument is weaker because under the HISA statute, there is a process for appealing any sanction based on an investigation of a rule violation–it can go up through a well-established administrative appeal process with federal administrative law judges, who are the ones hearing the appeal.  That means that no punishment is final until it is ruled on by a federal official.

TDN: What you're saying is the Congressional amendment potentially has influence on the overall constitutionality of HISA beyond that one provision it was designed to fix…

LF: Yes. Congress's amendments to HISA responded only to what the Fifth Circuit had found to be the problems. But those problems were kind of an umbrella. The fifth Circuit issue was: Did the statute give too much regulatory authority to the private Authority? Congress's amendment has addressed that and clarified that the FTC is now a lot more than a rubber stamp.

And so, if a judge now decides that that congressional amendment makes the HISA structure much closer to the SEC structure–which has been upheld as constitutional, including the way in which people are appointed to the private entity, FINRA, and in its investigatory authority–then it is more likely that the other challenges to HISA would not be accepted.

Although, let me clarify. There is a difference with the SEC's process for investigating alleged violations of its rules. The SEC has its own government employees doing the investigations and the initial determinations. Under the HISA statute, the initial investigations and determinations are not done by FTC government employees–they're done by employees of the private Authority. That is still a potential challenge which has been raised in some of the lawsuits around the country.

TDN: Do you think this action might have any influence on the FTC's pending decision on whether or not to approve HISA's ADMC rules?

LF: I don't think it will. I mean, as soon as Congress amended the statute, the FTC said, 'now we're going to go ahead with the rulemaking process on the medication rules.' That is a strong signal.

Right now, we have a situation where the groups that are opposed to HISA have been throwing every legal argument they can think of at the statute, hoping that something sticks. Well, something did stick with the Fifth Circuit and Congress responded to that. So now, all the groups that are opposed to HISA are going to try to argue back in the district courts that the congressional fix isn't enough, and to then throw other arguments against HISA.

There's a long litigation road ahead for the statute and the Authority. I think I'm going to start calling the HISA statute the 'full employment for the lawyers' statute. The real people benefiting are the lawyers getting all these cases.

TDN: Given the swirling legal uncertainty, if the FTC approves the ADMC rules and they go into effect, will the Authority be leaving itself open to strong legal challenges when the first medication violation adjudications come rolling in?

LF: Well, let me put it this way. Trainers that have been sanctioned under the old system of each state determining its rules and sanctions have shown a propensity for hiring as many lawyers as they can to appeal and try to get their penalties reduced or vacated. Why would that change just because the penalty is for a HISA rule as opposed to a state commission rule?

TDN: And running up against the federal government is a little different than running up against a state commission?

LF: Yes, and that may be one of the things that the various HBPAs are worried about.

TDN: The Texas Racing Commission stated that the recent Fifth Circuit Court of Appeals action means that HISA has no jurisdictional authority in the state, and therefore, they can beam their simulcasting signal out-of-state once more. The Sam Houston lawyers are more circumspect. Who's right?

LF: The Fifth Circuit did not issue an injunction against the statute and rules. It was just what's called a declaratory judgment. So, there is not currently any binding legal order that applies in Texas that prohibits HISA from acting.  The HISA statute applies to any entity that simulcasts into other states, so if any Texas track does start sending its signal to other states, it will be subject to HISA unless a court issues an injunction prohibiting HISA from acting.

But should HISA try to enforce any regulations in Texas, whoever was the target of any enforcement could sue to get an injunction saying, 'you can't enforce your rules if this circuit said you're unconstitutional.' So, in a roundabout way, the Texas Racing Commission is correct but–and this is a big but–only for the superseded version of HISA before the congressional amendments. If the courts rule that the congressional amendments fix the problem found by the Fifth Circuit then they would not enjoin HISA from acting in Texas. So I think the circumspection of the lawyers for Sam Houston is warranted.

Eventually, where is this all going in Texas or any other objecting state? It's becoming a game of whack-a-mole. The Fifth Circuit says this part of HISA is unconstitutional. Congress fixes it. Now, some other court says, 'another part of HISA is unconstitutional.' Well, Congress could then fix that. All of the challenges to HISA are delaying implementation, but ultimately, I do not think they will not stop the movement towards uniform national rules for the multi-state business of horse racing.

TDN: There's another case in the Northern District of Texas, Amarillo. Do you know what's happening with the case-and do you still think this could prove a major headache for HISA this year?

LF: There's been no further decisions in that court. That judge has to follow the Fifth Circuit decision on the challenge to the previous version of HISA about the allocation of responsibility between the FTC and the private Authority. Before that Judge, HISA and the FTC will argue that the newly amended statute satisfies the Fifth Circuit concerns, and that judge could allow the newly amended rules to go into effect. But as I said in our previous conversation, that case in Amarillo does have a lot of other challenges to HISA, such as to the way members of the Authority are appointed and the investigatory process and powers given to HISA.

If you file a case in the Amarillo branch of the Federal District Court for that part of Texas, you get Judge [Matthew] Kacsmaryk. He has quickly gained a reputation based on his rulings for being very hostile to broad federal regulation, and he has all kinds of hot button issues being brought to him, asking him to undo often decades of federal regulatory schemes. So, that's why I said it's the case that could become a major headache for HISA, because that case would get appealed to the Fifth Circuit which has already shown scepticism about the extent to which Congress delegates federal power to a private entity.

TDN: Where does this leave the pending ruling in the Sixth Circuit?

LF: The Sixth Circuit, because they haven't ruled yet, has more options before them based on the congressional amendment. The Sixth Circuit asked the lawyers to submit briefs addressing how the congressional amendment affected the appeal. The Sixth Circuit could say, 'well, the HISA statute has changed in significant ways. We want to let the district court start afresh and assess the parties' arguments based on the new statute.'

There really doesn't seem to be a lot of point for the Sixth Circuit to issue an opinion about whether they think a now superseded version of the statute is constitutional. So, I think it is likely that the Sixth Circuit will decide the appeal before them is moot and send it back to the district court, where the HISA and FTC lawyers will try to persuade the district court judge that the congressional amendments do solve all the constitutional concerns that the Fifth Circuit raised.

TDN: Do you think HISA is right to forge on with implementation of the full program (pending FTC approval), or do you think it would behoove them to put the breaks on while all the legal shenanigans play out?

LF: This is asking for my personal opinion–I'm trying to provide an impartial legal view. But I think that yes, the HISA Authority is pursuing the right course. Remember, several states have voluntarily agreed to follow their rules. So, for those states who've said, 'we participate in this, we want to follow your rules,' these rules need to be developed.

This is maybe getting a little too deep into the weeds, but the judge in Amarillo is famous for issuing nationwide injunctions. If the judge in Amarillo were to do that, then HISA would be legally prohibited from implementing its rules anywhere. But in the meantime, there isn't a national injunction, so, why wouldn't they continue knowing that there are a substantial number of states–including some of the most prestigious racetracks and racing circuits in the country–that want to follow their uniform rules?

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Weekly Stewards and Commissions Rulings, Jan. 24-30

Every week, the TDN publishes a roundup of key official rulings from the primary tracks within the four major racing jurisdictions of California, New York, Florida and Kentucky.

Here's a primer on how each of these jurisdictions adjudicates different offenses, what they make public (or not) and where.

With the Horseracing Integrity and Safety Act (HISA) having gone into effect on July 1, the TDN will also post a roundup of the relevant HISA-related rulings from the same week.

California
Track: Santa Anita
Date: 01/22/2023
Licensee: Randy Rennon, owner
Penalty: Suspended license
Violation: Failure to comply with financial agreement
Explainer: Owner Randy Rennon (dba Summer Knights Stables, Inc), having failed to comply with a Financial Agreement dated November 26, 2020, at Del Mar Race Track, is suspended for violation of California Horse Racing Board rule #1876 (Financial Responsibility – Farrier Kyle Baze $820.00). Suspension to commence on January 29, 2023.During the term of this suspension, all licenses and license privileges of Randy Rennon (dba Summer Knights Stables, Inc) are suspended and pursuant to California Horse Racing Board rule #1528 (Jurisdiction of Stewards), subject is denied access to all premises in this jurisdiction.

Track: Santa Anita
Date: 01/27/2023
Licensee: Rolando Quinonez, trainer
Penalty: $1,000 fine
Violation: Excessive use of whip during training hours
Explainer: Trainer Rolando Quinonez is fined $1,000.00 for violation of California Horse Racing Board rules #1874 (Disorderly Conduct – excessive use of riding crop during training) and #1530 (Cases Not Covered by Rules and Regulations) at San Luis Rey Training Center on September 14, 2022. Furthermore, Rolando Quinonez must be evaluated by the Winners Foundation for anger management and comply with any recommendations made by Winners Foundation.

NEW HISA STEWARDS RULINGS
The following rulings were reported on HISA's “rulings” portal, except for the voided claim rulings which were sent to the TDN directly. Some of these rulings are from prior weeks as they were not reported contemporaneously.
One important note: HISA's whip use limit is restricted to six strikes during a race.

Violations of Crop Rule
Aqueduct
Katherine “Katie” Davis – violation date January 20; $250 fine and one-day suspension, 7 strikes

Gulfstream Park
Shaun Bridgmohan – violation date January 21; $250 fine and one-day suspension, 7 strikes
Jaime Alexis Torres – violation date January 22; $250 fine, laceration on his mount Talking Like Mom from the crop

Oaklawn Park
Ramsey Zimmerman – violation date January 28; $250 fine and one-day suspension, 7 strikes
Ricardo Santana – violation date January 28; $250 fine, raising his wrist above his helmet when using the crop during the seventh race

Parx Racing
Anthony Salgado – violation date January 20; $250 fine and one-day suspension, 7 strikes

Penn National
Ricardo A Chiappe – violation date January 20; $250 fine and one-day suspension, 9 strikes

Tampa Bay Downs
Carlos Eduardo Rojas- violation date January 18; $250 fine and one-day suspension, 7 strikes
Carlos Eduardo Rojas – violation date January 18: Rojas has accumulated a total of 23 points for violations of HISA Rule 2280 (b), (1), though six of the points are under appeal and a stay has being granted, so the total points is reduced to 17 points. “Jockey Carlos E. Rojas is hereby suspended 15 calendar days based on points accumulated for multiple violations. To be serve from Wednesday, February 1st, 2023 through and including Wednesday, February 15, 2023.”

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Weekly Stewards and Commissions Rulings, January 17-23

Every week, the TDN publishes a roundup of key official rulings from the primary tracks within the four major racing jurisdictions of California, New York, Florida and Kentucky.

Here's a primer on how each of these jurisdictions adjudicates different offenses, what they make public (or not) and where.

With the Horseracing Integrity and Safety Act (HISA) having gone into effect on July 1, the TDN will also post a roundup of the relevant HISA-related rulings from the same week.

New York

Track: Aqueduct
Date: 01/18/2023
Licensee: Manuel Franco
Penalty: Three-day suspension
Violation: Mid-race interference
Explainer: For having waived his right to an appeal Jockey Mr. Manuel Franco is hereby suspended for 3 NYRA racing days January 20th 2023, January 21st 2023, January 22nd 2023 inclusive. This for interference during the running of the seventh race at Aqueduct Racetrack on January 12th 2023 causing his horse ” Spiked” to be disqualified from first and placed third.

Track: Aqueduct
Date: 01/19/2023
Licensee: Michelle Giangiulio, trainer
Penalty: Ten-day suspension, $1,000 fine
Violation: Medication violation
Explainer: Having received a report from the NYS Gaming Commission Drug Testing Laboratory of the finding of Phenylbutazone in the post-race sample taken from horse ” Eight and Sand ” (#10) which raced at Aqueduct racetrack in the 9th race and finished 1st on December 11th 2022. Trainer of record Ms. Michelle Giangiulio having been notified of the post-race findings and having waived her right to an appeal, is hereby fined the sum of one thousand ($1,000) dollars and suspended 10 Calendar days effective January 20th 2023, through January 29th 2023, inclusive. Furthermore, the Stewards order horse “Eight and Sand” disqualified from any part of the purse and the purse redistributed as follows:

1. (#12) Itsalittlebitfunny
2. (#3) Reunion Tour
3. (#6) Our Son Jake
4. (#7) Tiza Brown
5. (#11) Escape Mission
6. (#9) Patrick the Great
7. (#4) Dancing with Rico
8. (#1) Uncle Bruce
9. (#2) Hereby
10.(#8) Red Jet
11.(#5) Chief Engineer

Ordered that during your period of suspension, you shall not directly or indirectly participate in New York State Pari-mutuel horse racing. You are denied the privileges and use of the grounds of all racetracks, you are forbidden to participate in any share of purses or other payment. Every horse is denied the privileges of the grounds and shall not participate in pari-mutuel racing in New York State, that (a) is owned or trained by you, or by individuals who serves as your agent or employee during your suspension: or (b) for which you during your suspension are directly or indirectly with training, including any arrangements to care for, train, enter, race, invoice, collect fees or other payments, manage funds, employ or insure workers, provide advice or other information or otherwise assist with any aspect of the training of such horses.

NEW HISA STEWARDS RULINGS

The following rulings were reported on HISA's “rulings” portal, except for the voided claim rulings which were sent to the TDN directly. Some of these rulings are from prior weeks as they were not reported contemporaneously.

One important note: HISA's whip use limit is restricted to six strikes during a race.

Violations of Crop Rule

Aqueduct

Gherson (Jason) Huayas – violation date January 14; $250 fine and one-day suspension, 8 strikes

Abner Perez Adorno – violation date January 20; $250 fine and one-day suspension, 7 strikes

Golden Gate Fields

Silvio Amador – violation date January 16; $250 fine and one-day suspension, 7 strikes

Julien H Couton – violation date January 21; $250 fine and one-day suspension, 7 strikes

Gulfstream Park

Jorge Espitia – violation date January 14; $250 fine and one-day suspension, 7 strikes

Santa Anita

Frankie Dettori – violation date January 15; $250 fine and one-day suspension, 7 strikes

Victor Espinoza – violation date January 15; $250 fine and one-day suspension, 8 strikes

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