Equine Recurrent Uveitis And Appaloosas: What’s The Correlation?

Every Appaloosa over the age of 12 should have an eye exam to ensure the horse isn't suffering from equine recurrent uveitis (ERU) or moon blindness, a disease that disproportionately affects the breed. As the disease progresses, it can lead to blindness.

A study by Drs. Sandmeyer, Nicole Kingsley, Cheryl Walder, Sheila Archer, Marina Leis, Rebecca Bellone and Bianca Bauer completed a retrospective study using horses that were referred to the Western College of Veterinary Medicine in Canada.The research team found that ERU occurred 13 percent more often in Apps than in other breeds; of all horses at the hospital who had ERU, Appaloosas made up 62.5 percent of the ERU cases.

The study team then had board-certified ophthalmologists examine 145 Appaloosas on 11 farms in Western Canada to determine what risk factors Appaloosas have that may be relevant to ERU development. They sought to study if coat pattern correlated at all with ERU risk: Specifically, if Appaloosas that had extensive white were more at risk to develop ERU.

Horses were categorized as having no signs or mild, moderate or severe signs of ERU. Of the 145 horses examined, 20 (14%) were confirmed with ERU. The research team determined that:

  • ERU occurred 11 percent of the time in horses with few spots; 29 percent of the time in Apps with white blankets and no spots (called snowcap); 15 percent in leopard apps, which are white with spots all over; 11 percent on Apps with a white rump that has spots and 13 percent of the time in Apps with no patterning over the topline
  • There was no association between gender or base coat color and ERU
  • Age is a significant risk factor; 12.3 years old being the mean age of affected horses. For each year older, the odds of ERU increased 1.15 times
  • The study did not find ERU in horses that had white-flecked coats, lace blankets or solid coloration that does not roan with age
  • Apps with leopard spotting are at increased risk for ERU
  • A common ancestor was identified in 83 percent of affected horses within eight generations, and five were inbred to that ancestor

The scientists determined that many horses have chronic, low-grade clinical signs of ERU that go undetected until the condition worsens. Because of this, it's imperative that owners of Appaloosas have their eyes checked yearly, specifically after 12 years old.

Read more at EquiManagement.

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