Equine Metabolic Syndrome: A Horse Health Enigma

Similar to other companion animals, obesity in horses is common—it's estimated that between 20 and 70 percent of horses are overweight. Ponies have the highest risk of becoming overweight, followed by cob-type horses.

Obesity is also one of the most prevalent health conditions in humans.; it's associated with premature mortality, metabolic dysfunction and a myriad of health conditions. In horses, obesity-induced conditions include laminitis. Because of this, obesity is important to both human and equine medicine.

Drs. Natalie Wallis and Eleanor Raffan note that obesity regulation can be disrupted by both genetic and environmental factors. The heritability of obesity is high in humans and lab animals, with evidence showing the same in companion animals.

Laminitis is of significant concern as it is such a devastating disease. The risk factors that link obesity and laminitis are collectively called equine metabolic syndrome (EMS). EMS is defined as insulin dysregulation. Insulin resistance is common in EMS, but it's rare for horses and ponies to actually become diabetic.

Add to that discovery that not all overweight equines develop EMS, and EMS doesn't always cause laminitis. Last but not least, not all horses that have EMS are overweight. These paradoxes exist across breeds and between individuals, similar to humans, where there is variability between individuals and between ethnic groups.

The scientists concluded that obesity is a health concern of both humans and horses, and more research is needed on the molecular basis of obesity and associated metabolic conditions. They also note that veterinarians have much to learn about obesity from human genetics and laboratory animal models. They hope that by using both of these, animal studies will be fast tracked

Read the review here.

Read more at HorseTalk.

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Stakes Winner Honest Mischief Retired To Stud At Sequel Stallions

Stakes winning sprinter, Honest Mischief (Into Mischief – Honest Lady by Seattle Slew), has been retired to Sequel Stallions New York, where he will stand for a fee of $6,500 LFSN.

Bred and raced by leading global powerhouse, Juddmonte Farm, Honest Mischief broke his maiden in his second start by eight lengths at Keeneland becoming a TDN Rising Star and earning an outstanding 2 Ragozin Number. He became a stakes winner winning the Force The Pass City of Laurel Stakes and was second to the brilliantly fast Volatile in the Aristides Stakes at Churchill Downs. Honest Mischief became graded stakes-placed in the Grade 2 Amsterdam Stakes at Saratoga. He bested G1 stakes winners Mind Control and Complexity in the G1 Woody Stephens Stakes at Belmont. Honest Mischief retires with four wins, three seconds, and one third in nine career starts with earnings of $287,464.

“Honest Mischief identified himself very early as one of the best dirt prospects of his crop in our barn.” Said Chad Brown, Trainer. “He proved to be very fast, durable, and consistent in both the mornings and afternoons. He has all the qualities my really good Into Mischief's have. I have never had a horse run a 2 Ragozin Number so early in his 3-year-old year. He was very, very fast!”

Honest Mischief hails from one of the most significant families in the stud book today. His G1 stakes winning dam, Honest Lady, is a half-sister to 4 Graded Stakes winners including G1 Classic winner, Empire Maker, as well as sires, Chester House and Decarchy. Honest Lady established herself as one of the most important racehorses of her generation winning the G1 Santa Monica Handicap and running 2nd against colts in the Breeders' Cup Sprint. Honest Mischief is also the grandson of Broodmare Of The Year, Leslie's Lady, and Toussaud.

“Honest Mischief's pedigree epitomizes the simplistic Juddmonte approach of matching the world's best dirt stallion with Prince Khalid's best dirt family.” Said Garrett O'Rourke, Manager of Juddmonte Farm. “Honest Lady was a nose away from being a Breeders Cup Sprint G1 champion in the fastest ever Breeder's Cup Sprint. She also placed in a Met Mile G1 against colts, and was the most beautiful little mare with a regal personality. Then to be by Seattle Slew out of broodmare of the year, Toussaud, and dam of G1 winner, First Defense, illustrates the peerless quality of this pedigree. Honest Mischief was pegged as a real talent by our exercise riders from the very beginning. He had raw speed, he was sound, and he had desire. He placed behind stars like Shancelot and Volatile at the top of their games and when he won, he won like a G1 horse. Honest Mischief has such a genetic concentration of classic talent, on top and bottom of his pedigree, that expectation of his success at stud is just a given.”

“Into Mischief is the most dominant sire of our times, rocketing to stardom from the very ordinary mares originating from his first books. To stand at stud the son of such an incredible sire as well as the magnificent female family Honest Mischief exhibits is beyond exciting,” said Becky Thomas of Sequel New York. “I am a super fan of Into Mischief and am honored to bring Honest Mischief to New York with the support and participation of Juddmonte Farm.”

 

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Breeding Right in Mehmas (Ire) Tops Arqana Online

During the Nov. 24 sale of breeding rights and stallion shares on Arqana Online, a breeding right in champion first-season sire elect Mehmas (Ire) (Acclamation {GB}) (lot 2) brought €195,000 from Haras du Mont-dit-Mont. Already the sire of 48 winners, 10 black-type performers and four black-type winners led by G1 Middle Park S. hero Supremacy (Ire), the young stallion will command €25,000 at Tally-Ho Stud in 2021.

A breeding right to four-time Group 1 winner Golden Horn (GB) (Cape Cross {Ire}) (lot 3), whose oldest foals are three, went for €42,000 to Select Bloodstock. Also marked as sold were a breeding right in Due Diligence (War Front) (lot 5) to Haras Mont-dit-Mont for €6,000 and Blandford Bloodstock snapped up a breeding right to Group 1 winner Havana Grey (GB) (Havana Gold {Ire}) (lot 4) for €19,000.

The only lot that was unsold was a 1/50th share in champion Almanzor (Fr) (Wootton Bassett {GB}) (lot 1)which RNA’d for €240,000.

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Tom’s Ready Arrives At Old Friends Retirement Center

Old Friends, the Thoroughbred Retirement Center in Georgetown, KY, is proud to welcome multiple graded stakes winner Tom's Ready. The 7-year-old son of More Than Ready — Goodbye Stranger, by Broad Brush stood initially at Spendthrift Farm and then at Red River Farms in Louisiana.

Bred in Pennsylvania and campaigned by the late Tom Benson's GMB Racing and trainer Dallas Stewart, Tom's Ready broke his maiden in his third start as a 2-year-old at Churchill Downs, and followed that win with a close 2nd in the Street Sense Stakes. A second-place finish to Gun Runner in the Louisiana Derby (G2), qualified Tom's Ready for the Kentucky Derby, where he finished 12th behind winner Nyquist. His career apex came the following year when he captured the 2016 $500,000 Woody Stephens Stakes (G2) at Belmont Park.  He went on to defeat older horses, including champion sprinter Runhappy, in the Ack Ack Stakes (G3), again at Churchill. He ended the season with a fifth-place finish in the Breeders' Cup Dirt Mile. At 4, he captured the Leemat Stakes at Presque Isle Downs and the Bold Ruler Handicap (G3) at Belmont Park. Tom's Ready retires with earnings of $1,036,267.

“I truly respect and appreciate the great work of the staff at Old Friends as we have come to know Michael Blowen and his great work,” said GMB Racing's Gayle Benson. “We have had St. Aloysius there for a number of years, and it gives us great pleasure to have our wonderful Tom's Ready retire to Old Friends. He was our first purchase, he is a Grade II winner, and he raced in the Kentucky Derby and the Breeder's Cup, so we are very proud of him and he is deserving of the great care that Old Friends will provide.”

“We're honored to add Tom's Ready to our other old friends,” said Old Friends founder and President Michael Blowen. “I'm certain that his many fans will be very excited to see him when we, hopefully, open for tours post-virus. Meanwhile, he already has his head in the carrot bucket.”

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